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MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity.
Yacoub A, Mitchell C, Brannon J, Rosenberg E, Qiao L, McKinstry R, Linehan WM, Su ZS, Sarkar D, Lebedeva IV, Valerie K, Gopalkrishnan RV, Grant S, Fisher PB, Dent P. Yacoub A, et al. Among authors: gopalkrishnan rv. Mol Cancer Ther. 2003 Jul;2(7):623-32. Mol Cancer Ther. 2003. PMID: 12883035
MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.
Yacoub A, Mitchell C, Hong Y, Gopalkrishnan RV, Su ZZ, Gupta P, Sauane M, Lebedeva IV, Curiel DT, Mahasreshti PJ, Rosenfeld MR, Broaddus WC, James CD, Grant S, Fisher PB, Dent P. Yacoub A, et al. Among authors: gopalkrishnan rv. Cancer Biol Ther. 2004 Aug;3(8):739-51. doi: 10.4161/cbt.3.8.968. Epub 2004 Aug 10. Cancer Biol Ther. 2004. PMID: 15197348 Free article.
mda-7/IL-24: exploiting cancer's Achilles' heel.
Lebedeva IV, Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Gupta P, Nemunaitis J, Cunningham C, Yacoub A, Dent P, Fisher PB. Lebedeva IV, et al. Among authors: gopalkrishnan rv. Mol Ther. 2005 Jan;11(1):4-18. doi: 10.1016/j.ymthe.2004.08.012. Mol Ther. 2005. PMID: 15585401 Free article. Review.
mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.
Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Valerie K, Dent P, Fisher PB. Sarkar D, et al. Among authors: gopalkrishnan rv. Proc Natl Acad Sci U S A. 2002 Jul 23;99(15):10054-9. doi: 10.1073/pnas.152327199. Epub 2002 Jul 11. Proc Natl Acad Sci U S A. 2002. PMID: 12114539 Free PMC article.
35 results