Suhara Y - Search Results

1

Design, synthesis, and biological studies of the A-ring-modified 1,25-dihydroxyvitamin D3 analogs.

Takayama H, Kittaka A, Fujishima T, Suhara Y. Takayama H, et al. Among authors: suhara y. Recent Results Cancer Res. 2003;164:289-317. doi: 10.1007/978-3-642-55580-0_21. Recent Results Cancer Res. 2003. PMID: 12899530 Review.

2

Synthesis and testing of 2alpha-modified 1alpha,25-dihydroxyvitamin D(3) analogues with a double side chain: marked cell differentiation activity.

Suhara Y, Kittaka A, Kishimoto S, Calverley MJ, Fujishima T, Saito N, Sugiura T, Waku K, Takayama H. Suhara Y, et al. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3255-8. doi: 10.1016/s0960-894x(02)00722-9. Bioorg Med Chem Lett. 2002. PMID: 12392726

3

Design and efficient synthesis of new stable 1alpha,25-dihydroxy-19-norvitamin D3 analogues containing amide bond.

Suhara Y, Kittaka A, Ono K, Kurihara M, Fujishima T, Yoshida A, Takayama H. Suhara Y, et al. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3533-6. doi: 10.1016/s0960-894x(02)00800-4. Bioorg Med Chem Lett. 2002. PMID: 12443770

4

2 alpha-(3-hydroxypropyl)- and 2 alpha-(3-hydroxypropoxy)-1 alpha,25-dihydroxyvitamin D3 accessible to vitamin D receptor mutant related to hereditary vitamin D-resistant rickets.

Kittaka A, Kurihara M, Peleg S, Suhara Y, Takayama H. Kittaka A, et al. Among authors: suhara y. Chem Pharm Bull (Tokyo). 2003 Mar;51(3):357-8. doi: 10.1248/cpb.51.357. Chem Pharm Bull (Tokyo). 2003. PMID: 12612432 Free article.

5

Efficient synthesis of 2-modified 1alpha,25-dihydroxy-19-norvitamin D3 with Julia olefination: high potency in induction of differentiation on HL-60 cells.

Ono K, Yoshida A, Saito N, Fujishima T, Honzawa S, Suhara Y, Kishimoto S, Sugiura T, Waku K, Takayama H, Kittaka A. Ono K, et al. Among authors: suhara y. J Org Chem. 2003 Sep 19;68(19):7407-15. doi: 10.1021/jo034787y. J Org Chem. 2003. PMID: 12968893

6

Concise synthesis and biological activities of 2alpha-alkyl- and 2alpha-(omega-hydroxyalkyl)-20-epi-1alpha,25-dihydroxyvitamin D3.

Honzawa S, Suhara Y, Nihei K, Saito N, Kishimoto S, Fujishima T, Kurihara M, Sugiura T, Waku K, Takayama H, Kittaka A. Honzawa S, et al. Among authors: suhara y. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3503-6. doi: 10.1016/s0960-894x(03)00739-x. Bioorg Med Chem Lett. 2003. PMID: 14505658

7

Design and efficient synthesis of 2 alpha-(omega-hydroxyalkoxy)-1 alpha,25-dihydroxyvitamin D3 Analogues, including 2-epi-ED-71 and their 20-epimers with HL-60 cell differentiation activity.

Saito N, Suhara Y, Kurihara M, Fujishima T, Honzawa S, Takayanagi H, Kozono T, Matsumoto M, Ohmori M, Miyata N, Takayama H, Kittaka A. Saito N, et al. Among authors: suhara y. J Org Chem. 2004 Oct 29;69(22):7463-71. doi: 10.1021/jo0491051. J Org Chem. 2004. PMID: 15497970

8

Biological activities of 2alpha-substituted analogues of 1alpha,25-dihydroxyvitamin D3 in transcriptional regulation and human promyelocytic leukemia (HL-60) cell proliferation and differentiation.

Takahashi E, Nakagawa K, Suhara Y, Kittaka A, Nihei K, Konno K, Takayama H, Ozono K, Okano T. Takahashi E, et al. Among authors: suhara y. Biol Pharm Bull. 2006 Nov;29(11):2246-50. doi: 10.1248/bpb.29.2246. Biol Pharm Bull. 2006. PMID: 17077522 Free article.

9

Synthesis and biological evaluation of several structural analogs of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand.

Suhara Y, Oka S, Kittaka A, Takayama H, Waku K, Sugiura T. Suhara Y, et al. Bioorg Med Chem. 2007 Jan 15;15(2):854-67. doi: 10.1016/j.bmc.2006.10.049. Epub 2006 Oct 27. Bioorg Med Chem. 2007. PMID: 17110113

10

Synthesis of 2alpha-propoxy-1alpha,25-dihydroxyvitamin D3 and comparison of its metabolism by human CYP24A1 and rat CYP24A1.

Saito N, Suhara Y, Abe D, Kusudo T, Ohta M, Yasuda K, Sakaki T, Honzawa S, Fujishima T, Kittaka A. Saito N, et al. Among authors: suhara y. Bioorg Med Chem. 2009 Jul 1;17(13):4296-301. doi: 10.1016/j.bmc.2009.05.032. Epub 2009 May 18. Bioorg Med Chem. 2009. PMID: 19482479

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