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Phase I and pharmacokinetic study of Yondelis (Ecteinascidin-743; ET-743) administered as an infusion over 1 h or 3 h every 21 days in patients with solid tumours.
Twelves C, Hoekman K, Bowman A, Vermorken JB, Anthoney A, Smyth J, van Kesteren C, Beijnen JH, Uiters J, Wanders J, Gomez J, Guzmán C, Jimeno J, Hanauske A. Twelves C, et al. Among authors: vermorken jb. Eur J Cancer. 2003 Sep;39(13):1842-51. doi: 10.1016/s0959-8049(03)00458-1. Eur J Cancer. 2003. PMID: 12932661 Clinical Trial.
Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study.
van Kesteren C, Twelves C, Bowman A, Hoekman K, López-Lázaro L, Jimeno J, Guzman C, Mathôt RA, Simpson A, Vermorken JB, Smyth J, Schellens JH, Hillebrand MJ, Rosing H, Beijnen JH. van Kesteren C, et al. Among authors: vermorken jb. Anticancer Drugs. 2002 Apr;13(4):381-93. doi: 10.1097/00001813-200204000-00007. Anticancer Drugs. 2002. PMID: 11984084 Clinical Trial.
Phase I study of vintriptol, a tryptophan ester of vinblastine.
Oosterkamp HM, Vlasveld LT, Wanders J, Beijnen JH, van Tellingen O, Dubbelman AC, Simonetti GP, Franklin HR, Vermorken JB, Ten Bokkel Huinink WW. Oosterkamp HM, et al. Among authors: vermorken jb. Eur J Cancer. 1991;27(10):1222-6. doi: 10.1016/0277-5379(91)90085-r. Eur J Cancer. 1991. PMID: 1835590 Clinical Trial.
Clinical phase II study and pharmacological evaluation of rubitecan in non-pretreated patients with metastatic colorectal cancer-significant effect of food intake on the bioavailability of the oral camptothecin analogue.
Schöffski P, Herr A, Vermorken JB, Van den Brande J, Beijnen JH, Rosing H, Volk J, Ganser A, Adank S, Botma HJ, Wanders J. Schöffski P, et al. Among authors: vermorken jb. Eur J Cancer. 2002 Apr;38(6):807-13. doi: 10.1016/s0959-8049(02)00022-9. Eur J Cancer. 2002. PMID: 11937315 Clinical Trial.
Analysis of Ecteinascidin 743, a new potent marine-derived anticancer drug, in human plasma by high-performance liquid chromatography in combination with solid-phase extraction.
Rosing H, Hillebrand MJ, Jimeno JM, Gómez A, Floriano P, Faircloth G, Cameron L, Henrar RE, Vermorken JB, Bult A, Beijnen JH. Rosing H, et al. Among authors: vermorken jb. J Chromatogr B Biomed Sci Appl. 1998 Jun 12;710(1-2):183-9. doi: 10.1016/s0378-4347(98)00143-1. J Chromatogr B Biomed Sci Appl. 1998. PMID: 9686886
Quantitative determination of Ecteinascidin 743 in human plasma by miniaturized high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Rosing H, Hillebrand MJ, Jimeno JM, Gómez A, Floriano P, Faircloth G, Henrar RE, Vermorken JB, Cvitkovic E, Bult A, Beijnen JH. Rosing H, et al. Among authors: vermorken jb. J Mass Spectrom. 1998 Nov;33(11):1134-40. doi: 10.1002/(SICI)1096-9888(1998110)33:11<1134::AID-JMS730>3.0.CO;2-S. J Mass Spectrom. 1998. PMID: 9835068 Clinical Trial.
Pharmacokinetics of paclitaxel administered as a 3-hour or 96-hour infusion.
Panday VR, ten Bokkel Huinink WW, Vermorken JB, Rosing H, Koopman FJ, Swart M, Schellens JH, Beijnen JH. Panday VR, et al. Among authors: vermorken jb. Pharmacol Res. 1999 Jul;40(1):67-74. doi: 10.1006/phrs.1999.0477. Pharmacol Res. 1999. PMID: 10378993 Clinical Trial.
Pharmacologic study of paclitaxel administered with or without the cytoprotective agent amifostine, and given as a single agent or in combination with epirubicin and cisplatin in patients with advanced solid tumors.
Van den Brande J, Nannan Panday VR, Hoekman K, Rosing H, Huijskes RV, Verheijen RH, Beijnen JH, Vermorken JB. Van den Brande J, et al. Among authors: vermorken jb. Am J Clin Oncol. 2001 Aug;24(4):401-3. doi: 10.1097/00000421-200108000-00020. Am J Clin Oncol. 2001. PMID: 11474273
560 results