Parlow JJ - Search Results

1

Polymer-assisted solution-phase library synthesis and crystal structure of alpha-ketothiazoles as tissue factor VIIa inhibitors.

Parlow JJ, Dice TA, Lachance RM, Girard TJ, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, South MS. Parlow JJ, et al. J Med Chem. 2003 Sep 11;46(19):4043-9. doi: 10.1021/jm030130t. J Med Chem. 2003. PMID: 12954057

2

Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.

South MS, Case BL, Wood RS, Jones DE, Hayes MJ, Girard TJ, Lachance RM, Nicholson NS, Clare M, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, Parlow JJ. South MS, et al. Among authors: parlow jj. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2319-25. doi: 10.1016/s0960-894x(03)00410-4. Bioorg Med Chem Lett. 2003. PMID: 12824026

3

Polymer-assisted solution-phase (PASP) parallel synthesis of an alpha-ketothiazole library as tissue factor VIIa inhibitors.

South MS, Dice TA, Girard TJ, Lachance RM, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, Parlow JJ. South MS, et al. Among authors: parlow jj. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2363-7. doi: 10.1016/s0960-894x(03)00398-6. Bioorg Med Chem Lett. 2003. PMID: 12824035

4

Design, parallel synthesis, and crystal structures of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.

Parlow JJ, Case BL, Dice TA, Fenton RL, Hayes MJ, Jones DE, Neumann WL, Wood RS, Lachance RM, Girard TJ, Nicholson NS, Clare M, Stegeman RA, Stevens AM, Stallings WC, Kurumbail RG, South MS. Parlow JJ, et al. J Med Chem. 2003 Sep 11;46(19):4050-62. doi: 10.1021/jm030131l. J Med Chem. 2003. PMID: 12954058

5

Synthesis and crystal structures of substituted benzenes and benzoquinones as tissue factor VIIa inhibitors.

Parlow JJ, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, South MS. Parlow JJ, et al. J Med Chem. 2003 Sep 25;46(20):4297-312. doi: 10.1021/jm030233b. J Med Chem. 2003. PMID: 13678408

6

Synthesis and X-ray crystal structures of substituted fluorobenzene and benzoquinone inhibitors of the tissue factor VIIa complex.

Parlow JJ, Kurumbail RG, Stegeman RA, Stevens AM, Stallings WC, South MS. Parlow JJ, et al. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3721-5. doi: 10.1016/j.bmcl.2003.08.002. Bioorg Med Chem Lett. 2003. PMID: 14552766

7

Design, synthesis, and crystal structure of selective 2-pyridone tissue factor VIIa inhibitors.

Parlow JJ, Kurumbail RG, Stegeman RA, Stevens AM, Stallings WC, South MS. Parlow JJ, et al. J Med Chem. 2003 Oct 23;46(22):4696-701. doi: 10.1021/jm0301686. J Med Chem. 2003. PMID: 14561089

8

Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.

Parlow JJ, Burney MW, Case BL, Girard TJ, Hall KA, Hiebsch RR, Huff RM, Lachance RM, Mischke DA, Rapp SR, Woerndle RS, Ennis MD. Parlow JJ, et al. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4657-63. doi: 10.1016/j.bmcl.2009.06.075. Epub 2009 Jun 25. Bioorg Med Chem Lett. 2009. PMID: 19604694

9

Part II: piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.

Parlow JJ, Burney MW, Case BL, Girard TJ, Hall KA, Harris PK, Hiebsch RR, Huff RM, Lachance RM, Mischke DA, Rapp SR, Woerndle RS, Ennis MD. Parlow JJ, et al. Bioorg Med Chem Lett. 2010 Feb 15;20(4):1388-94. doi: 10.1016/j.bmcl.2009.12.110. Epub 2010 Jan 4. Bioorg Med Chem Lett. 2010. PMID: 20097563

10

Piperazinyl glutamate pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.

Parlow JJ, Burney MW, Case BL, Girard TJ, Hall KA, Harris PK, Hiebsch RR, Huff RM, Lachance RM, Mischke DA, Rapp SR, Woerndle RS, Ennis MD. Parlow JJ, et al. J Med Chem. 2010 Mar 11;53(5):2010-37. doi: 10.1021/jm901518t. J Med Chem. 2010. PMID: 20141147

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