Desmyter J - Search Results

1

TIBO derivatives: a new class of highly potent and specific inhibitors of HIV-1 replication.

Pauwels R, Andries K, Debyser Z, Kukla M, Schols D, Desmyter J, De Clercq E, Janssen PA. Pauwels R, et al. Among authors: desmyter j. Biochem Soc Trans. 1992 May;20(2):509-12. doi: 10.1042/bst0200509. Biochem Soc Trans. 1992. PMID: 1383063 Review. No abstract available.

2

Resistance of human immunodeficiency virus type 1 reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis.

de Vreese K, Debyser Z, Vandamme AM, Pauwels R, Desmyter J, de Clercq E, Anné J. de Vreese K, et al. Among authors: desmyter j. Virology. 1992 Jun;188(2):900-4. doi: 10.1016/0042-6822(92)90550-9. Virology. 1992. PMID: 1374986

3

Differential inhibitory effects of TIBO derivatives on different strains of simian immunodeficiency virus.

Debyser Z, De Vreese K, Pauwels R, Yamamoto N, Anné J, De Clercq E, Desmyter J. Debyser Z, et al. Among authors: desmyter j. J Gen Virol. 1992 Jul;73 ( Pt 7):1799-804. doi: 10.1099/0022-1317-73-7-1799. J Gen Virol. 1992. PMID: 1378481

4

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives.

Pauwels R, Andries K, Desmyter J, Schols D, Kukla MJ, Breslin HJ, Raeymaeckers A, Van Gelder J, Woestenborghs R, Heykants J, et al. Pauwels R, et al. Among authors: desmyter j. Nature. 1990 Feb 1;343(6257):470-4. doi: 10.1038/343470a0. Nature. 1990. PMID: 1689015

5

An antiviral target on reverse transcriptase of human immunodeficiency virus type 1 revealed by tetrahydroimidazo-[4,5,1-jk] [1,4]benzodiazepin-2 (1H)-one and -thione derivatives.

Debyser Z, Pauwels R, Andries K, Desmyter J, Kukla M, Janssen PA, De Clercq E. Debyser Z, et al. Among authors: desmyter j. Proc Natl Acad Sci U S A. 1991 Feb 15;88(4):1451-5. doi: 10.1073/pnas.88.4.1451. Proc Natl Acad Sci U S A. 1991. PMID: 1705038 Free PMC article.

6

Phosphonylmethoxyethyl purine derivatives, a new class of anti-human immunodeficiency virus agents.

Pauwels R, Balzarini J, Schols D, Baba M, Desmyter J, Rosenberg I, Holy A, De Clercq E. Pauwels R, et al. Among authors: desmyter j. Antimicrob Agents Chemother. 1988 Jul;32(7):1025-30. doi: 10.1128/AAC.32.7.1025. Antimicrob Agents Chemother. 1988. PMID: 2847636 Free PMC article.

7

New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs.

Pauwels R, Andries K, Debyser Z, Kukla MJ, Schols D, Breslin HJ, Woestenborghs R, Desmyter J, Janssen MA, De Clercq E, et al. Pauwels R, et al. Among authors: desmyter j. Antimicrob Agents Chemother. 1994 Dec;38(12):2863-70. doi: 10.1128/AAC.38.12.2863. Antimicrob Agents Chemother. 1994. PMID: 7535037 Free PMC article.

8

Investigations on the anti-HIV activity of 2',3'-dideoxyadenosine analogues with modifications in either the pentose or purine moiety. Potent and selective anti-HIV activity of 2,6-diaminopurine 2',3'-dideoxyriboside.

Pauwels R, Baba M, Balzarini J, Herdewijn P, Desmyter J, Robins MJ, Zou RM, Madej D, De Clercq E. Pauwels R, et al. Among authors: desmyter j. Biochem Pharmacol. 1988 Apr 1;37(7):1317-25. doi: 10.1016/0006-2952(88)90789-7. Biochem Pharmacol. 1988. PMID: 3258516

9

Allosteric inhibition of human immunodeficiency virus type 1 reverse transcriptase by tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione compounds.

Debyser Z, Pauwels R, Andries K, Desmyter J, Engelborghs Y, Janssen PA, De Clercq E. Debyser Z, et al. Among authors: desmyter j. Mol Pharmacol. 1992 Jan;41(1):203-8. Mol Pharmacol. 1992. PMID: 1370707

10

Common features in the interaction of tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one and -thione and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives with the human immunodeficiency virus type 1 reverse transcriptase.

Debyser Z, Pauwels R, Baba M, Desmyter J, De Clercq E. Debyser Z, et al. Among authors: desmyter j. Mol Pharmacol. 1992 May;41(5):963-8. Mol Pharmacol. 1992. PMID: 1375320

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