Albert VR - Search Results

1

The remarkable flexibility of the human antibody repertoire; isolation of over one thousand different antibodies to a single protein, BLyS.

Edwards BM, Barash SC, Main SH, Choi GH, Minter R, Ullrich S, Williams E, Du Fou L, Wilton J, Albert VR, Ruben SM, Vaughan TJ. Edwards BM, et al. Among authors: albert vr. J Mol Biol. 2003 Nov 14;334(1):103-18. doi: 10.1016/j.jmb.2003.09.054. J Mol Biol. 2003. PMID: 14596803

2

Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator.

Baker KP, Edwards BM, Main SH, Choi GH, Wager RE, Halpern WG, Lappin PB, Riccobene T, Abramian D, Sekut L, Sturm B, Poortman C, Minter RR, Dobson CL, Williams E, Carmen S, Smith R, Roschke V, Hilbert DM, Vaughan TJ, Albert VR. Baker KP, et al. Among authors: albert vr. Arthritis Rheum. 2003 Nov;48(11):3253-65. doi: 10.1002/art.11299. Arthritis Rheum. 2003. PMID: 14613291 Free article.

3

Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism.

Dobson CL, Main S, Newton P, Chodorge M, Cadwallader K, Humphreys R, Albert V, Vaughan TJ, Minter RR, Edwards BM. Dobson CL, et al. MAbs. 2009 Nov-Dec;1(6):552-62. doi: 10.4161/mabs.1.6.10057. Epub 2009 Nov 11. MAbs. 2009. PMID: 20068388 Free PMC article.

4

BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases.

Roschke V, Sosnovtseva S, Ward CD, Hong JS, Smith R, Albert V, Stohl W, Baker KP, Ullrich S, Nardelli B, Hilbert DM, Migone TS. Roschke V, et al. J Immunol. 2002 Oct 15;169(8):4314-21. doi: 10.4049/jimmunol.169.8.4314. J Immunol. 2002. PMID: 12370363

5

HGS-ETR1, a fully human TRAIL-receptor 1 monoclonal antibody, induces cell death in multiple tumour types in vitro and in vivo.

Pukac L, Kanakaraj P, Humphreys R, Alderson R, Bloom M, Sung C, Riccobene T, Johnson R, Fiscella M, Mahoney A, Carrell J, Boyd E, Yao XT, Zhang L, Zhong L, von Kerczek A, Shepard L, Vaughan T, Edwards B, Dobson C, Salcedo T, Albert V. Pukac L, et al. Br J Cancer. 2005 Apr 25;92(8):1430-41. doi: 10.1038/sj.bjc.6602487. Br J Cancer. 2005. PMID: 15846298 Free PMC article.

6

Monoclonal antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 (TRAIL-R2) induces apoptosis in primary renal cell carcinoma cells in vitro and inhibits tumor growth in vivo.

Zeng Y, Wu XX, Fiscella M, Shimada O, Humphreys R, Albert V, Kakehi Y. Zeng Y, et al. Int J Oncol. 2006 Feb;28(2):421-30. doi: 10.3892/ijo.28.2.421. Int J Oncol. 2006. PMID: 16391797

7

Activity of selective fully human agonistic antibodies to the TRAIL death receptors TRAIL-R1 and TRAIL-R2 in primary and cultured lymphoma cells: induction of apoptosis and enhancement of doxorubicin- and bortezomib-induced cell death.

Georgakis GV, Li Y, Humphreys R, Andreeff M, O'Brien S, Younes M, Carbone A, Albert V, Younes A. Georgakis GV, et al. Br J Haematol. 2005 Aug;130(4):501-10. doi: 10.1111/j.1365-2141.2005.05656.x. Br J Haematol. 2005. PMID: 16098063 Free article.

8

Human agonistic antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2 induces cytotoxicity and apoptosis in prostate cancer and bladder cancer cells.

Shimada O, Wu X, Jin X, Nouh MA, Fiscella M, Albert V, Matsuda T, Kakehi Y. Shimada O, et al. Urology. 2007 Feb;69(2):395-401. doi: 10.1016/j.urology.2006.12.007. Urology. 2007. PMID: 17320696

9

Enhanced apoptosis and tumor regression induced by a direct agonist antibody to tumor necrosis factor-related apoptosis-inducing ligand receptor 2.

Motoki K, Mori E, Matsumoto A, Thomas M, Tomura T, Humphreys R, Albert V, Muto M, Yoshida H, Aoki M, Tamada T, Kuroki R, Yoshida H, Ishida I, Ware CF, Kataoka S. Motoki K, et al. Clin Cancer Res. 2005 Apr 15;11(8):3126-35. doi: 10.1158/1078-0432.CCR-04-1867. Clin Cancer Res. 2005. PMID: 15837769

10

A humanized monoclonal antibody targeting the β7 integrin selectively blocks intestinal homing of T lymphocytes.

Stefanich EG, Danilenko DM, Wang H, O'Byrne S, Erickson R, Gelzleichter T, Hiraragi H, Chiu H, Ivelja S, Jeet S, Gadkari S, Hwang O, Fuh F, Looney C, Howell K, Albert V, Balazs M, Refino C, Fong S, Iyer S, Williams M. Stefanich EG, et al. Br J Pharmacol. 2011 Apr;162(8):1855-70. doi: 10.1111/j.1476-5381.2011.01205.x. Br J Pharmacol. 2011. PMID: 21232034 Free PMC article.

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