Tang JX - Search Results

1

A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif.

Kandimalla ER, Bhagat L, Zhu FG, Yu D, Cong YP, Wang D, Tang JX, Tang JY, Knetter CF, Lien E, Agrawal S. Kandimalla ER, et al. Among authors: tang jx, tang jy. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14303-8. doi: 10.1073/pnas.2335947100. Epub 2003 Nov 10. Proc Natl Acad Sci U S A. 2003. PMID: 14610275 Free PMC article.

2

Modulation of ovalbumin-induced Th2 responses by second-generation immunomodulatory oligonucleotides in mice.

Zhu FG, Kandimalla ER, Yu D, Tang JX, Agrawal S. Zhu FG, et al. Among authors: tang jx. Int Immunopharmacol. 2004 Jul;4(7):851-62. doi: 10.1016/j.intimp.2004.03.009. Int Immunopharmacol. 2004. PMID: 15182725

3

Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity.

Wang D, Kandimalla ER, Yu D, Tang JX, Agrawal S. Wang D, et al. Among authors: tang jx. Vaccine. 2005 Apr 8;23(20):2614-22. doi: 10.1016/j.vaccine.2004.11.028. Vaccine. 2005. PMID: 15780444

4

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.

Kandimalla ER, Bhagat L, Li Y, Yu D, Wang D, Cong YP, Song SS, Tang JX, Sullivan T, Agrawal S. Kandimalla ER, et al. Among authors: tang jx. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6925-30. doi: 10.1073/pnas.0501729102. Epub 2005 Apr 28. Proc Natl Acad Sci U S A. 2005. PMID: 15860583 Free PMC article.

5

Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8.

Lan T, Kandimalla ER, Yu D, Bhagat L, Li Y, Wang D, Zhu F, Tang JX, Putta MR, Cong Y, Trombino AF, Sullivan T, Agrawal S. Lan T, et al. Among authors: tang jx. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13750-5. doi: 10.1073/pnas.0706059104. Epub 2007 Aug 14. Proc Natl Acad Sci U S A. 2007. PMID: 17698957 Free PMC article.

6

Agonists of Toll-like receptor 9 containing synthetic dinucleotide motifs.

Yu D, Putta MR, Bhagat L, Li Y, Zhu F, Wang D, Tang JX, Kandimalla ER, Agrawal S. Yu D, et al. Among authors: tang jx. J Med Chem. 2007 Dec 13;50(25):6411-8. doi: 10.1021/jm070881l. Epub 2007 Nov 8. J Med Chem. 2007. PMID: 17988082

7

Conjugation of ligands at the 5'-end of CpG DNA affects immunostimulatory activity.

Kandimalla ER, Bhagat L, Yu D, Cong Y, Tang J, Agrawal S. Kandimalla ER, et al. Bioconjug Chem. 2002 Sep-Oct;13(5):966-74. doi: 10.1021/bc0200374. Bioconjug Chem. 2002. PMID: 12236778

8

Design, synthesis, and immunostimulatory properties of CpG DNAs containing alkyl-linker substitutions: role of nucleosides in the flanking sequences.

Yu D, Kandimalla ER, Cong Y, Tang J, Tang JY, Zhao Q, Agrawal S. Yu D, et al. J Med Chem. 2002 Sep 26;45(20):4540-8. doi: 10.1021/jm0201619. J Med Chem. 2002. PMID: 12238933

9

'Immunomers'--novel 3'-3'-linked CpG oligodeoxyribonucleotides as potent immunomodulatory agents.

Yu D, Kandimalla ER, Bhagat L, Tang JY, Cong Y, Tang J, Agrawal S. Yu D, et al. Nucleic Acids Res. 2002 Oct 15;30(20):4460-9. doi: 10.1093/nar/gkf582. Nucleic Acids Res. 2002. PMID: 12384593 Free PMC article.

10

CpG penta- and hexadeoxyribonucleotides as potent immunomodulatory agents.

Bhagat L, Zhu FG, Yu D, Tang J, Wang H, Kandimalla ER, Zhang R, Agrawal S. Bhagat L, et al. Biochem Biophys Res Commun. 2003 Jan 24;300(4):853-61. doi: 10.1016/s0006-291x(02)02943-1. Biochem Biophys Res Commun. 2003. PMID: 12559951

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