Wang D - Search Results

1

A dinucleotide motif in oligonucleotides shows potent immunomodulatory activity and overrides species-specific recognition observed with CpG motif.

Kandimalla ER, Bhagat L, Zhu FG, Yu D, Cong YP, Wang D, Tang JX, Tang JY, Knetter CF, Lien E, Agrawal S. Kandimalla ER, et al. Among authors: wang d. Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14303-8. doi: 10.1073/pnas.2335947100. Epub 2003 Nov 10. Proc Natl Acad Sci U S A. 2003. PMID: 14610275 Free PMC article.

2

Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.

Kandimalla ER, Bhagat L, Wang D, Yu D, Zhu FG, Tang J, Wang H, Huang P, Zhang R, Agrawal S. Kandimalla ER, et al. Among authors: wang h, wang d. Nucleic Acids Res. 2003 May 1;31(9):2393-400. doi: 10.1093/nar/gkg343. Nucleic Acids Res. 2003. PMID: 12711684 Free PMC article.

3

Immunopharmacological and antitumor effects of second-generation immunomodulatory oligonucleotides containing synthetic CpR motifs.

Wang D, Li Y, Yu D, Song SS, Kandimalla ER, Agrawal S. Wang D, et al. Int J Oncol. 2004 Apr;24(4):901-8. Int J Oncol. 2004. PMID: 15010828

4

Oral administration of second-generation immunomodulatory oligonucleotides induces mucosal Th1 immune responses and adjuvant activity.

Wang D, Kandimalla ER, Yu D, Tang JX, Agrawal S. Wang D, et al. Vaccine. 2005 Apr 8;23(20):2614-22. doi: 10.1016/j.vaccine.2004.11.028. Vaccine. 2005. PMID: 15780444

5

Immunomodulatory oligonucleotides containing a cytosine-phosphate-2'-deoxy-7-deazaguanosine motif as potent toll-like receptor 9 agonists.

Kandimalla ER, Bhagat L, Li Y, Yu D, Wang D, Cong YP, Song SS, Tang JX, Sullivan T, Agrawal S. Kandimalla ER, et al. Among authors: wang d. Proc Natl Acad Sci U S A. 2005 May 10;102(19):6925-30. doi: 10.1073/pnas.0501729102. Epub 2005 Apr 28. Proc Natl Acad Sci U S A. 2005. PMID: 15860583 Free PMC article.

6

Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8.

Lan T, Kandimalla ER, Yu D, Bhagat L, Li Y, Wang D, Zhu F, Tang JX, Putta MR, Cong Y, Trombino AF, Sullivan T, Agrawal S. Lan T, et al. Among authors: wang d. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13750-5. doi: 10.1073/pnas.0706059104. Epub 2007 Aug 14. Proc Natl Acad Sci U S A. 2007. PMID: 17698957 Free PMC article.

7

Agonists of Toll-like receptor 9 containing synthetic dinucleotide motifs.

Yu D, Putta MR, Bhagat L, Li Y, Zhu F, Wang D, Tang JX, Kandimalla ER, Agrawal S. Yu D, et al. Among authors: wang d. J Med Chem. 2007 Dec 13;50(25):6411-8. doi: 10.1021/jm070881l. Epub 2007 Nov 8. J Med Chem. 2007. PMID: 17988082

8

Modifications incorporated in CpG motifs of oligodeoxynucleotides lead to antagonist activity of toll-like receptors 7 and 9.

Yu D, Wang D, Zhu FG, Bhagat L, Dai M, Kandimalla ER, Agrawal S. Yu D, et al. Among authors: wang d. J Med Chem. 2009 Aug 27;52(16):5108-14. doi: 10.1021/jm900730r. J Med Chem. 2009. PMID: 19650625

9

Novel immunomodulatory oligonucleotides prevent development of allergic airway inflammation and airway hyperresponsiveness in asthma.

Agrawal DK, Edwan J, Kandimalla ER, Yu D, Bhagat L, Wang D, Agrawal S. Agrawal DK, et al. Among authors: wang d. Int Immunopharmacol. 2004 Jan;4(1):127-38. doi: 10.1016/j.intimp.2003.11.005. Int Immunopharmacol. 2004. PMID: 14975367

10

Impact of secondary structure of toll-like receptor 9 agonists on interferon alpha induction.

Yu D, Putta MR, Bhagat L, Dai M, Wang D, Trombino AF, Sullivan T, Kandimalla ER, Agrawal S. Yu D, et al. Among authors: wang d. Antimicrob Agents Chemother. 2008 Dec;52(12):4320-5. doi: 10.1128/AAC.00701-08. Epub 2008 Oct 13. Antimicrob Agents Chemother. 2008. PMID: 18852281 Free PMC article.

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