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A luminescent biosensor with increased dynamic range for intracellular cAMP.
Binkowski BF, Butler BL, Stecha PF, Eggers CT, Otto P, Zimmerman K, Vidugiris G, Wood MG, Encell LP, Fan F, Wood KV. Binkowski BF, et al. Among authors: wood mg, wood kv. ACS Chem Biol. 2011 Nov 18;6(11):1193-7. doi: 10.1021/cb200248h. Epub 2011 Sep 22. ACS Chem Biol. 2011. PMID: 21932825
Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate.
Hall MP, Unch J, Binkowski BF, Valley MP, Butler BL, Wood MG, Otto P, Zimmerman K, Vidugiris G, Machleidt T, Robers MB, Benink HA, Eggers CT, Slater MR, Meisenheimer PL, Klaubert DH, Fan F, Encell LP, Wood KV. Hall MP, et al. Among authors: wood mg, wood kv. ACS Chem Biol. 2012 Nov 16;7(11):1848-57. doi: 10.1021/cb3002478. Epub 2012 Aug 30. ACS Chem Biol. 2012. PMID: 22894855 Free PMC article.
HaloTag: a novel protein labeling technology for cell imaging and protein analysis.
Los GV, Encell LP, McDougall MG, Hartzell DD, Karassina N, Zimprich C, Wood MG, Learish R, Ohana RF, Urh M, Simpson D, Mendez J, Zimmerman K, Otto P, Vidugiris G, Zhu J, Darzins A, Klaubert DH, Bulleit RF, Wood KV. Los GV, et al. Among authors: wood mg, wood kv. ACS Chem Biol. 2008 Jun 20;3(6):373-82. doi: 10.1021/cb800025k. ACS Chem Biol. 2008. PMID: 18533659
Target engagement and drug residence time can be observed in living cells with BRET.
Robers MB, Dart ML, Woodroofe CC, Zimprich CA, Kirkland TA, Machleidt T, Kupcho KR, Levin S, Hartnett JR, Zimmerman K, Niles AL, Ohana RF, Daniels DL, Slater M, Wood MG, Cong M, Cheng YQ, Wood KV. Robers MB, et al. Among authors: wood mg, wood kv. Nat Commun. 2015 Dec 3;6:10091. doi: 10.1038/ncomms10091. Nat Commun. 2015. PMID: 26631872 Free PMC article.
122 results