Ankarcrona M - Search Results

1

Gamma-secretase activity of presenilin 1 regulates acetylcholine muscarinic receptor-mediated signal transduction.

Popescu BO, Cedazo-Minguez A, Benedikz E, Nishimura T, Winblad B, Ankarcrona M, Cowburn RF. Popescu BO, et al. Among authors: ankarcrona m. J Biol Chem. 2004 Feb 20;279(8):6455-64. doi: 10.1074/jbc.M306041200. Epub 2003 Nov 18. J Biol Chem. 2004. PMID: 14625299 Free article.

We previously showed that the FAD mutation causing an exon 9 deletion in PS1 results in enhanced basal phospholipase C (PLC) activity (Cedazo-Minguez, A., Popescu, B. O., Ankarcrona, M., Nishimura, T., and Cowburn, R. F. (2002) J. Biol. Chem. 277, 36646-36655). ...

We previously showed that the FAD mutation causing an exon 9 deletion in PS1 results in enhanced basal phospholipase C (PLC) activity (Cedaz …

2

Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines.

Dypbukt JM, Ankarcrona M, Burkitt M, Sjöholm A, Ström K, Orrenius S, Nicotera P. Dypbukt JM, et al. Among authors: ankarcrona m. J Biol Chem. 1994 Dec 2;269(48):30553-60. J Biol Chem. 1994. PMID: 7982974 Free article.

3

Alzheimer's disease presenilin-1 exon 9 deletion and L250S mutations sensitize SH-SY5Y neuroblastoma cells to hyperosmotic stress-induced apoptosis.

Tanii H, Ankarcrona M, Flood F, Nilsberth C, Mehta ND, Perez-Tur J, Winblad B, Benedikz E, Cowburn RF. Tanii H, et al. Among authors: ankarcrona m. Neuroscience. 2000;95(2):593-601. doi: 10.1016/s0306-4522(99)00432-7. Neuroscience. 2000. PMID: 10658639

4

Calcium ionophore A23187 specifically decreases the secretion of beta-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures.

Sennvik K, Benedikz E, Fastbom J, Sundström E, Winblad B, Ankarcrona M. Sennvik K, et al. Among authors: ankarcrona m. J Neurosci Res. 2001 Mar 1;63(5):429-37. doi: 10.1002/1097-4547(20010301)63:5<429::AID-JNR1038>3.0.CO;2-U. J Neurosci Res. 2001. PMID: 11223918

5

Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells.

Popescu BO, Cedazo-Minguez A, Popescu LM, Winblad B, Cowburn RF, Ankarcrona M. Popescu BO, et al. Among authors: ankarcrona m. J Neurosci Res. 2001 Oct 1;66(1):122-34. doi: 10.1002/jnr.1204. J Neurosci Res. 2001. PMID: 11599009

6

Neurons bearing presenilins: weapons for defense or suicide?

Popescu BO, Ankarcrona M. Popescu BO, et al. Among authors: ankarcrona m. J Cell Mol Med. 2000 Oct-Dec;4(4):249-261. doi: 10.1111/j.1582-4934.2000.tb00124.x. J Cell Mol Med. 2000. PMID: 12067459 Free PMC article.

7

Presenilin-1 is located in rat mitochondria.

Ankarcrona M, Hultenby K. Ankarcrona M, et al. Biochem Biophys Res Commun. 2002 Jul 19;295(3):766-70. doi: 10.1016/s0006-291x(02)00735-0. Biochem Biophys Res Commun. 2002. PMID: 12099705

8

The presenilin 1 deltaE9 mutation gives enhanced basal phospholipase C activity and a resultant increase in intracellular calcium concentrations.

Cedazo-Minguez A, Popescu BO, Ankarcrona M, Nishimura T, Cowburn RF. Cedazo-Minguez A, et al. Among authors: ankarcrona m. J Biol Chem. 2002 Sep 27;277(39):36646-55. doi: 10.1074/jbc.M112117200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121968 Free article.

9

Mechanisms of cell death in Alzheimer's disease: role of presenilins.

Popescu BO, Ankarcrona M. Popescu BO, et al. Among authors: ankarcrona m. J Alzheimers Dis. 2004 Apr;6(2):123-8. doi: 10.3233/jad-2004-6203. J Alzheimers Dis. 2004. PMID: 15096695 Review.

10

Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria.

Hansson CA, Frykman S, Farmery MR, Tjernberg LO, Nilsberth C, Pursglove SE, Ito A, Winblad B, Cowburn RF, Thyberg J, Ankarcrona M. Hansson CA, et al. Among authors: ankarcrona m. J Biol Chem. 2004 Dec 3;279(49):51654-60. doi: 10.1074/jbc.M404500200. Epub 2004 Sep 28. J Biol Chem. 2004. PMID: 15456764 Free article.

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