Murphy G - Search Results

1

Evidence for a critical role of the tumor necrosis factor alpha convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR).

Weskamp G, Schlöndorff J, Lum L, Becherer JD, Kim TW, Saftig P, Hartmann D, Murphy G, Blobel CP. Weskamp G, et al. Among authors: murphy g. J Biol Chem. 2004 Feb 6;279(6):4241-9. doi: 10.1074/jbc.M307974200. Epub 2003 Nov 24. J Biol Chem. 2004. PMID: 14638693 Free article.

2

Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx.

Horiuchi K, Le Gall S, Schulte M, Yamaguchi T, Reiss K, Murphy G, Toyama Y, Hartmann D, Saftig P, Blobel CP. Horiuchi K, et al. Among authors: murphy g. Mol Biol Cell. 2007 Jan;18(1):176-88. doi: 10.1091/mbc.e06-01-0014. Epub 2006 Nov 1. Mol Biol Cell. 2007. PMID: 17079736 Free PMC article.

3

Full-length and N-TIMP-3 display equal inhibitory activities toward TNF-alpha convertase.

Lee MH, Knäuper V, Becherer JD, Murphy G. Lee MH, et al. Among authors: murphy g. Biochem Biophys Res Commun. 2001 Jan 26;280(3):945-50. doi: 10.1006/bbrc.2000.4192. Biochem Biophys Res Commun. 2001. PMID: 11162616

4

The C-terminal domains of TACE weaken the inhibitory action of N-TIMP-3.

Lee MH, Verma V, Maskos K, Becherer JD, Knäuper V, Dodds P, Amour A, Murphy G. Lee MH, et al. Among authors: murphy g. FEBS Lett. 2002 Jun 5;520(1-3):102-6. doi: 10.1016/s0014-5793(02)02776-x. FEBS Lett. 2002. PMID: 12044879 Free article.

5

The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs.

Amour A, Knight CG, English WR, Webster A, Slocombe PM, Knäuper V, Docherty AJ, Becherer JD, Blobel CP, Murphy G. Amour A, et al. Among authors: murphy g. FEBS Lett. 2002 Jul 31;524(1-3):154-8. doi: 10.1016/s0014-5793(02)03047-8. FEBS Lett. 2002. PMID: 12135759 Free article.

6

Tumor necrosis factor-alpha-converting enzyme (TACE/ADAM-17) mediates the ectodomain cleavage of intercellular adhesion molecule-1 (ICAM-1).

Tsakadze NL, Sithu SD, Sen U, English WR, Murphy G, D'Souza SE. Tsakadze NL, et al. Among authors: murphy g. J Biol Chem. 2006 Feb 10;281(6):3157-64. doi: 10.1074/jbc.M510797200. Epub 2005 Dec 6. J Biol Chem. 2006. PMID: 16332693 Free article.

7

Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme.

Lee MH, Rapti M, Murphy G. Lee MH, et al. Among authors: murphy g. J Biol Chem. 2004 Oct 22;279(43):45121-9. doi: 10.1074/jbc.M406611200. Epub 2004 Aug 12. J Biol Chem. 2004. PMID: 15308656 Free article.

8

Membrane type 4 matrix metalloproteinase (MMP17) has tumor necrosis factor-alpha convertase activity but does not activate pro-MMP2.

English WR, Puente XS, Freije JM, Knauper V, Amour A, Merryweather A, Lopez-Otin C, Murphy G. English WR, et al. Among authors: murphy g. J Biol Chem. 2000 May 12;275(19):14046-55. doi: 10.1074/jbc.275.19.14046. J Biol Chem. 2000. PMID: 10799478 Free article.

9

The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family.

Apte SS, Olsen BR, Murphy G. Apte SS, et al. Among authors: murphy g. J Biol Chem. 1995 Jun 16;270(24):14313-8. doi: 10.1074/jbc.270.24.14313. J Biol Chem. 1995. PMID: 7782289 Free article.

10

Up-regulation of vascular endothelial growth factor-A by active membrane-type 1 matrix metalloproteinase through activation of Src-tyrosine kinases.

Sounni NE, Roghi C, Chabottaux V, Janssen M, Munaut C, Maquoi E, Galvez BG, Gilles C, Frankenne F, Murphy G, Foidart JM, Noel A. Sounni NE, et al. Among authors: murphy g. J Biol Chem. 2004 Apr 2;279(14):13564-74. doi: 10.1074/jbc.M307688200. Epub 2004 Jan 16. J Biol Chem. 2004. PMID: 14729679 Free article.

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