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Normal lysosomal morphology and function in LAMP-1-deficient mice.
Andrejewski N, Punnonen EL, Guhde G, Tanaka Y, Lüllmann-Rauch R, Hartmann D, von Figura K, Saftig P. Andrejewski N, et al. Among authors: saftig p. J Biol Chem. 1999 Apr 30;274(18):12692-701. doi: 10.1074/jbc.274.18.12692. J Biol Chem. 1999. PMID: 10212251 Free article.
Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency.
Herreman A, Hartmann D, Annaert W, Saftig P, Craessaerts K, Serneels L, Umans L, Schrijvers V, Checler F, Vanderstichele H, Baekelandt V, Dressel R, Cupers P, Huylebroeck D, Zwijsen A, Van Leuven F, De Strooper B. Herreman A, et al. Among authors: saftig p. Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11872-7. doi: 10.1073/pnas.96.21.11872. Proc Natl Acad Sci U S A. 1999. PMID: 10518543 Free PMC article.
Implication of APP secretases in notch signaling.
Hartmann D, Tournoy J, Saftig P, Annaert W, De Strooper B. Hartmann D, et al. Among authors: saftig p. J Mol Neurosci. 2001 Oct;17(2):171-81. doi: 10.1385/JMN:17:2:171. J Mol Neurosci. 2001. PMID: 11816790 Review.
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.
Hundhausen C, Misztela D, Berkhout TA, Broadway N, Saftig P, Reiss K, Hartmann D, Fahrenholz F, Postina R, Matthews V, Kallen KJ, Rose-John S, Ludwig A. Hundhausen C, et al. Among authors: saftig p. Blood. 2003 Aug 15;102(4):1186-95. doi: 10.1182/blood-2002-12-3775. Epub 2003 Apr 24. Blood. 2003. PMID: 12714508 Free article.
346 results