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Inactivated whole-virus vaccine derived from a proviral DNA clone of simian immunodeficiency virus induces high levels of neutralizing antibodies and confers protection against heterologous challenge.
Johnson PR, Montefiori DC, Goldstein S, Hamm TE, Zhou J, Kitov S, Haigwood NL, Misher L, London WT, Gerin JL, et al. Johnson PR, et al. Among authors: misher l. Proc Natl Acad Sci U S A. 1992 Mar 15;89(6):2175-9. doi: 10.1073/pnas.89.6.2175. Proc Natl Acad Sci U S A. 1992. PMID: 1549578 Free PMC article.
Sequential immunization with a subtype B HIV-1 envelope quasispecies partially mimics the in vivo development of neutralizing antibodies.
Malherbe DC, Doria-Rose NA, Misher L, Beckett T, Puryear WB, Schuman JT, Kraft Z, O'Malley J, Mori M, Srivastava I, Barnett S, Stamatatos L, Haigwood NL. Malherbe DC, et al. Among authors: misher l. J Virol. 2011 Jun;85(11):5262-74. doi: 10.1128/JVI.02419-10. Epub 2011 Mar 23. J Virol. 2011. PMID: 21430056 Free PMC article.
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