Le Beau MM - Search Results

1

Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.

Braun BS, Tuveson DA, Kong N, Le DT, Kogan SC, Rozmus J, Le Beau MM, Jacks TE, Shannon KM. Braun BS, et al. Among authors: le dt, le beau mm. Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):597-602. doi: 10.1073/pnas.0307203101. Epub 2003 Dec 29. Proc Natl Acad Sci U S A. 2004. PMID: 14699048 Free PMC article.

2

Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder.

Le DT, Kong N, Zhu Y, Lauchle JO, Aiyigari A, Braun BS, Wang E, Kogan SC, Le Beau MM, Parada L, Shannon KM. Le DT, et al. Among authors: le beau mm. Blood. 2004 Jun 1;103(11):4243-50. doi: 10.1182/blood-2003-08-2650. Epub 2004 Feb 24. Blood. 2004. PMID: 14982883 Free article.

3

Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation.

Phan VT, Shultz DB, Truong BT, Blake TJ, Brown AL, Gonda TJ, Le Beau MM, Kogan SC. Phan VT, et al. Among authors: le beau mm. Mol Cell Biol. 2003 Jul;23(13):4573-85. doi: 10.1128/MCB.23.13.4573-4585.2003. Mol Cell Biol. 2003. PMID: 12808098 Free PMC article.

4

Tumor suppressor gene inactivation in myeloid malignancies.

Wong JC, Le Beau MM, Shannon K. Wong JC, et al. Among authors: le beau mm. Best Pract Res Clin Haematol. 2008 Dec;21(4):601-14. doi: 10.1016/j.beha.2008.09.001. Best Pract Res Clin Haematol. 2008. PMID: 19041599 Review.

5

Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies.

Wong JC, Zhang Y, Lieuw KH, Tran MT, Forgo E, Weinfurtner K, Alzamora P, Kogan SC, Akagi K, Wolff L, Le Beau MM, Killeen N, Shannon K. Wong JC, et al. Among authors: le beau mm. Blood. 2010 Jun 3;115(22):4524-32. doi: 10.1182/blood-2009-07-232504. Epub 2010 Mar 16. Blood. 2010. PMID: 20233966 Free PMC article.

6

Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation.

Xu J, Haigis KM, Firestone AJ, McNerney ME, Li Q, Davis E, Chen SC, Nakitandwe J, Downing J, Jacks T, Le Beau MM, Shannon K. Xu J, et al. Among authors: le beau mm. Cancer Discov. 2013 Sep;3(9):993-1001. doi: 10.1158/2159-8290.CD-13-0096. Epub 2013 Jun 3. Cancer Discov. 2013. PMID: 23733505 Free PMC article.

7

Modeling myeloid leukemia tumor suppressor gene inactivation in the mouse.

Shannon KM, Le Beau MM, Largaespada DA, Killeen N. Shannon KM, et al. Among authors: le beau mm. Semin Cancer Biol. 2001 Jun;11(3):191-200. doi: 10.1006/scbi.2001.0372. Semin Cancer Biol. 2001. PMID: 11407944 Review.

8

RAS, FLT3, and TP53 mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7.

Side LE, Curtiss NP, Teel K, Kratz C, Wang PW, Larson RA, Le Beau MM, Shannon KM. Side LE, et al. Among authors: le beau mm. Genes Chromosomes Cancer. 2004 Mar;39(3):217-23. doi: 10.1002/gcc.10320. Genes Chromosomes Cancer. 2004. PMID: 14732923

9

HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo.

Fischbach NA, Rozenfeld S, Shen W, Fong S, Chrobak D, Ginzinger D, Kogan SC, Radhakrishnan A, Le Beau MM, Largman C, Lawrence HJ. Fischbach NA, et al. Among authors: le beau mm. Blood. 2005 Feb 15;105(4):1456-66. doi: 10.1182/blood-2004-04-1583. Epub 2004 Nov 2. Blood. 2005. PMID: 15522959 Free article.

10

Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia.

Jones L, Wei G, Sevcikova S, Phan V, Jain S, Shieh A, Wong JC, Li M, Dubansky J, Maunakea ML, Ochoa R, Zhu G, Tennant TR, Shannon KM, Lowe SW, Le Beau MM, Kogan SC. Jones L, et al. Among authors: le beau mm. J Exp Med. 2010 Nov 22;207(12):2581-94. doi: 10.1084/jem.20091071. Epub 2010 Nov 8. J Exp Med. 2010. PMID: 21059853 Free PMC article.

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