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1,2,4-triazolo[4,3-a]quinoxalin-1-one moiety as an attractive scaffold to develop new potent and selective human A3 adenosine receptor antagonists: synthesis, pharmacological, and ligand-receptor modeling studies.
Colotta V, Catarzi D, Varano F, Calabri FR, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Deflorian F, Moro S. Colotta V, et al. Among authors: martini c. J Med Chem. 2004 Jul 1;47(14):3580-90. doi: 10.1021/jm031136l. J Med Chem. 2004. PMID: 15214785
1,2,4-Triazolo[1,5-a]quinoxaline as a versatile tool for the design of selective human A3 adenosine receptor antagonists: synthesis, biological evaluation, and molecular modeling studies of 2-(hetero)aryl- and 2-carboxy-substituted derivatives.
Catarzi D, Colotta V, Varano F, Lenzi O, Filacchioni G, Trincavelli L, Martini C, Montopoli C, Moro S. Catarzi D, et al. Among authors: martini c. J Med Chem. 2005 Dec 15;48(25):7932-45. doi: 10.1021/jm0504149. J Med Chem. 2005. PMID: 16335918
4-amido-2-aryl-1,2,4-triazolo[4,3-a]quinoxalin-1-ones as new potent and selective human A3 adenosine receptor antagonists. synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Lenzi O, Colotta V, Catarzi D, Varano F, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Varani K, Marighetti F, Morizzo E, Moro S. Lenzi O, et al. Among authors: martini c. J Med Chem. 2006 Jun 29;49(13):3916-25. doi: 10.1021/jm060373w. J Med Chem. 2006. PMID: 16789747
New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Colotta V, Catarzi D, Varano F, Capelli F, Lenzi O, Filacchioni G, Martini C, Trincavelli L, Ciampi O, Pugliese AM, Pedata F, Schiesaro A, Morizzo E, Moro S. Colotta V, et al. Among authors: martini c. J Med Chem. 2007 Aug 23;50(17):4061-74. doi: 10.1021/jm070123v. Epub 2007 Aug 1. J Med Chem. 2007. PMID: 17665891
1,048 results