Burk O - Search Results

1

Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens.

von Richter O, Burk O, Fromm MF, Thon KP, Eichelbaum M, Kivistö KT. von Richter O, et al. Among authors: burk o. Clin Pharmacol Ther. 2004 Mar;75(3):172-83. doi: 10.1016/j.clpt.2003.10.008. Clin Pharmacol Ther. 2004. PMID: 15001968

2

Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters.

Glaeser H, Drescher S, van der Kuip H, Behrens C, Geick A, Burk O, Dent J, Somogyi A, Von Richter O, Griese EU, Eichelbaum M, Fromm MF. Glaeser H, et al. Among authors: burk o. Clin Pharmacol Ther. 2002 Mar;71(3):131-40. doi: 10.1067/mcp.2002.121370. Clin Pharmacol Ther. 2002. PMID: 11907487 Clinical Trial.

3

Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor.

Burk O, Arnold KA, Nussler AK, Schaeffeler E, Efimova E, Avery BA, Avery MA, Fromm MF, Eichelbaum M. Burk O, et al. Mol Pharmacol. 2005 Jun;67(6):1954-65. doi: 10.1124/mol.104.009019. Epub 2005 Mar 10. Mol Pharmacol. 2005. PMID: 15761118

4

Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.

Becquemont L, Glaeser H, Drescher S, Hitzl M, Simon N, Murdter TE, Heinkele G, Hofmann U, Schaefer C, Burk O, Verstuyft C, Eichelbaum M, Fromm MF. Becquemont L, et al. Among authors: burk o. Clin Pharmacol Ther. 2006 May;79(5):449-60. doi: 10.1016/j.clpt.2006.01.005. Epub 2006 Apr 11. Clin Pharmacol Ther. 2006. PMID: 16678547 Clinical Trial.

5

Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein.

Pauli-Magnus C, von Richter O, Burk O, Ziegler A, Mettang T, Eichelbaum M, Fromm MF. Pauli-Magnus C, et al. Among authors: burk o. J Pharmacol Exp Ther. 2000 May;293(2):376-82. J Pharmacol Exp Ther. 2000. PMID: 10773005

6

The effect of rifampin treatment on intestinal expression of human MRP transporters.

Fromm MF, Kauffmann HM, Fritz P, Burk O, Kroemer HK, Warzok RW, Eichelbaum M, Siegmund W, Schrenk D. Fromm MF, et al. Among authors: burk o. Am J Pathol. 2000 Nov;157(5):1575-80. doi: 10.1016/S0002-9440(10)64794-3. Am J Pathol. 2000. PMID: 11073816 Free PMC article.

7

Selective induction of human hepatic cytochromes P450 2B6 and 3A4 by metamizole.

Saussele T, Burk O, Blievernicht JK, Klein K, Nussler A, Nussler N, Hengstler JG, Eichelbaum M, Schwab M, Zanger UM. Saussele T, et al. Among authors: burk o. Clin Pharmacol Ther. 2007 Sep;82(3):265-74. doi: 10.1038/sj.clpt.6100138. Epub 2007 Mar 7. Clin Pharmacol Ther. 2007. PMID: 17344806

8

The impact of thyroid disease on the regulation, expression, and function of ABCB1 (MDR1/P glycoprotein) and consequences for the disposition of digoxin.

Burk O, Brenner SS, Hofmann U, Tegude H, Igel S, Schwab M, Eichelbaum M, Alscher MD. Burk O, et al. Clin Pharmacol Ther. 2010 Nov;88(5):685-94. doi: 10.1038/clpt.2010.176. Epub 2010 Sep 15. Clin Pharmacol Ther. 2010. PMID: 20844484

9

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

Burk O, Tegude H, Koch I, Hustert E, Wolbold R, Glaeser H, Klein K, Fromm MF, Nuessler AK, Neuhaus P, Zanger UM, Eichelbaum M, Wojnowski L. Burk O, et al. J Biol Chem. 2002 Jul 5;277(27):24280-8. doi: 10.1074/jbc.M202345200. Epub 2002 Apr 8. J Biol Chem. 2002. PMID: 11940601 Free article.

10

Sex is a major determinant of CYP3A4 expression in human liver.

Wolbold R, Klein K, Burk O, Nüssler AK, Neuhaus P, Eichelbaum M, Schwab M, Zanger UM. Wolbold R, et al. Among authors: burk o. Hepatology. 2003 Oct;38(4):978-88. doi: 10.1053/jhep.2003.50393. Hepatology. 2003. PMID: 14512885

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