Eichelbaum M - Search Results

1

Cytochrome P450 3A4 and P-glycoprotein expression in human small intestinal enterocytes and hepatocytes: a comparative analysis in paired tissue specimens.

von Richter O, Burk O, Fromm MF, Thon KP, Eichelbaum M, Kivistö KT. von Richter O, et al. Among authors: eichelbaum m. Clin Pharmacol Ther. 2004 Mar;75(3):172-83. doi: 10.1016/j.clpt.2003.10.008. Clin Pharmacol Ther. 2004. PMID: 15001968

2

Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters.

Glaeser H, Drescher S, van der Kuip H, Behrens C, Geick A, Burk O, Dent J, Somogyi A, Von Richter O, Griese EU, Eichelbaum M, Fromm MF. Glaeser H, et al. Among authors: eichelbaum m. Clin Pharmacol Ther. 2002 Mar;71(3):131-40. doi: 10.1067/mcp.2002.121370. Clin Pharmacol Ther. 2002. PMID: 11907487 Clinical Trial.

3

Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine.

Burk O, Tegude H, Koch I, Hustert E, Wolbold R, Glaeser H, Klein K, Fromm MF, Nuessler AK, Neuhaus P, Zanger UM, Eichelbaum M, Wojnowski L. Burk O, et al. Among authors: eichelbaum m. J Biol Chem. 2002 Jul 5;277(27):24280-8. doi: 10.1074/jbc.M202345200. Epub 2002 Apr 8. J Biol Chem. 2002. PMID: 11940601 Free article.

4

MDR1 gene polymorphisms and disposition of the P-glycoprotein substrate fexofenadine.

Drescher S, Schaeffeler E, Hitzl M, Hofmann U, Schwab M, Brinkmann U, Eichelbaum M, Fromm MF. Drescher S, et al. Among authors: eichelbaum m. Br J Clin Pharmacol. 2002 May;53(5):526-34. doi: 10.1046/j.1365-2125.2002.01591.x. Br J Clin Pharmacol. 2002. PMID: 11994059 Free PMC article. Clinical Trial.

5

Tissue-specific regulation of canine intestinal and hepatic phenol and morphine UDP-glucuronosyltransferases by beta-naphthoflavone in comparison with humans.

Bock KW, Bock-Hennig BS, Münzel PA, Brandenburg JO, Köhle CT, Soars MG, Riley RJ, Burchell B, von Richter O, Eichelbaum MF, Swedmark S, Orzechowski A. Bock KW, et al. Biochem Pharmacol. 2002 May 1;63(9):1683-90. doi: 10.1016/s0006-2952(02)00921-8. Biochem Pharmacol. 2002. PMID: 12007571

6

Genetic polymorphisms of glutathione S-transferase A1, the major glutathione S-transferase in human liver: consequences for enzyme expression and busulfan conjugation.

Bredschneider M, Klein K, Mürdter TE, Marx C, Eichelbaum M, Nüssler AK, Neuhaus P, Zanger UM, Schwab M. Bredschneider M, et al. Among authors: eichelbaum m. Clin Pharmacol Ther. 2002 Jun;71(6):479-87. doi: 10.1067/mcp.2002.124518. Clin Pharmacol Ther. 2002. PMID: 12087351

7

Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptibility to renal epithelial tumors.

Siegsmund M, Brinkmann U, Scháffeler E, Weirich G, Schwab M, Eichelbaum M, Fritz P, Burk O, Decker J, Alken P, Rothenpieler U, Kerb R, Hoffmeyer S, Brauch H. Siegsmund M, et al. Among authors: eichelbaum m. J Am Soc Nephrol. 2002 Jul;13(7):1847-54. doi: 10.1097/01.asn.0000019412.87412.bc. J Am Soc Nephrol. 2002. PMID: 12089380

8

Pharmacokinetics of intravenous etoposide in patients with breast cancer: influence of dose escalation and cyclophosphamide and doxorubicin coadministration.

Busse D, Würthwein G, Hinske C, Hempel G, Fromm MF, Eichelbaum M, Kroemer HK, Busch FW. Busse D, et al. Among authors: eichelbaum m. Naunyn Schmiedebergs Arch Pharmacol. 2002 Sep;366(3):218-25. doi: 10.1007/s00210-002-0594-2. Epub 2002 Jul 3. Naunyn Schmiedebergs Arch Pharmacol. 2002. PMID: 12172704 Clinical Trial.

9

Interindividual variability and tissue-specificity in the expression of cytochrome P450 3A mRNA.

Koch I, Weil R, Wolbold R, Brockmöller J, Hustert E, Burk O, Nuessler A, Neuhaus P, Eichelbaum M, Zanger U, Wojnowski L. Koch I, et al. Among authors: eichelbaum m. Drug Metab Dispos. 2002 Oct;30(10):1108-14. doi: 10.1124/dmd.30.10.1108. Drug Metab Dispos. 2002. PMID: 12228187

10

Genetic polymorphisms of the human MDR1 drug transporter.

Schwab M, Eichelbaum M, Fromm MF. Schwab M, et al. Among authors: eichelbaum m. Annu Rev Pharmacol Toxicol. 2003;43:285-307. doi: 10.1146/annurev.pharmtox.43.100901.140233. Epub 2002 Jan 10. Annu Rev Pharmacol Toxicol. 2003. PMID: 12359865 Review.

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