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Single-chain recombinant HLA-DQ2.5/peptide molecules block α2-gliadin-specific pathogenic CD4+ T-cell proliferation and attenuate production of inflammatory cytokines: a potential therapy for celiac disease.
Huan J, Meza-Romero R, Mooney JL, Vandenbark AA, Offner H, Burrows GG. Huan J, et al. Among authors: mooney jl. Mucosal Immunol. 2011 Jan;4(1):112-20. doi: 10.1038/mi.2010.44. Epub 2010 Aug 25. Mucosal Immunol. 2011. PMID: 20736999 Free PMC article.
A novel regulatory pathway for autoimmune disease: binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T-cell tolerance.
Vandenbark AA, Meza-Romero R, Benedek G, Andrew S, Huan J, Chou YK, Buenafe AC, Dahan R, Reiter Y, Mooney JL, Offner H, Burrows GG. Vandenbark AA, et al. Among authors: mooney jl. J Autoimmun. 2013 Feb;40:96-110. doi: 10.1016/j.jaut.2012.08.004. Epub 2012 Sep 29. J Autoimmun. 2013. PMID: 23026773 Free PMC article.
Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice.
Vandenbark AA, Rich C, Mooney J, Zamora A, Wang C, Huan J, Fugger L, Offner H, Jones R, Burrows GG. Vandenbark AA, et al. Among authors: mooney j. J Immunol. 2003 Jul 1;171(1):127-33. doi: 10.4049/jimmunol.171.1.127. J Immunol. 2003. PMID: 12816990
650 results