Spruck CH - Search Results

1

Cyclin E dysregulation and chromosomal instability in endometrial cancer.

Hubalek MM, Widschwendter A, Erdel M, Gschwendtner A, Fiegl HM, Müller HM, Goebel G, Mueller-Holzner E, Marth C, Spruck CH, Reed SI, Widschwendter M. Hubalek MM, et al. Among authors: spruck ch. Oncogene. 2004 May 20;23(23):4187-92. doi: 10.1038/sj.onc.1207560. Oncogene. 2004. PMID: 15048079

2

Detection of low molecular weight derivatives of cyclin E1 is a function of cyclin E1 protein levels in breast cancer.

Spruck C, Sun D, Fiegl H, Marth C, Mueller-Holzner E, Goebel G, Widschwendter M, Reed SI. Spruck C, et al. Cancer Res. 2006 Jul 15;66(14):7355-60. doi: 10.1158/0008-5472.CAN-05-3240. Cancer Res. 2006. PMID: 16849587

3

hCDC4 gene mutations in endometrial cancer.

Spruck CH, Strohmaier H, Sangfelt O, Müller HM, Hubalek M, Müller-Holzner E, Marth C, Widschwendter M, Reed SI. Spruck CH, et al. Cancer Res. 2002 Aug 15;62(16):4535-9. Cancer Res. 2002. PMID: 12183400

4

Mutation of hCDC4 leads to cell cycle deregulation of cyclin E in cancer.

Ekholm-Reed S, Spruck CH, Sangfelt O, van Drogen F, Mueller-Holzner E, Widschwendter M, Zetterberg A, Reed SI. Ekholm-Reed S, et al. Among authors: spruck ch. Cancer Res. 2004 Feb 1;64(3):795-800. doi: 10.1158/0008-5472.can-03-3417. Cancer Res. 2004. PMID: 14871801

5

Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints.

del Rincón SV, Widschwendter M, Sun D, Ekholm-Reed S, Tat J, Teixeira LK, Ellederova Z, Grolieres E, Reed SI, Spruck C. del Rincón SV, et al. Oncogene. 2015 Apr 9;34(15):1961-7. doi: 10.1038/onc.2014.137. Epub 2014 May 26. Oncogene. 2015. PMID: 24858038 Free PMC article.

6

Deregulated cyclin E induces chromosome instability.

Spruck CH, Won KA, Reed SI. Spruck CH, et al. Nature. 1999 Sep 16;401(6750):297-300. doi: 10.1038/45836. Nature. 1999. PMID: 10499591

7

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

Akhoondi S, Sun D, von der Lehr N, Apostolidou S, Klotz K, Maljukova A, Cepeda D, Fiegl H, Dafou D, Marth C, Mueller-Holzner E, Corcoran M, Dagnell M, Nejad SZ, Nayer BN, Zali MR, Hansson J, Egyhazi S, Petersson F, Sangfelt P, Nordgren H, Grander D, Reed SI, Widschwendter M, Sangfelt O, Spruck C. Akhoondi S, et al. Cancer Res. 2007 Oct 1;67(19):9006-12. doi: 10.1158/0008-5472.CAN-07-1320. Cancer Res. 2007. PMID: 17909001

8

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.

Strohmaier H, Spruck CH, Kaiser P, Won KA, Sangfelt O, Reed SI. Strohmaier H, et al. Among authors: spruck ch. Nature. 2001 Sep 20;413(6853):316-22. doi: 10.1038/35095076. Nature. 2001. PMID: 11565034

9

Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteins.

Liberal V, Martinsson-Ahlzén HS, Liberal J, Spruck CH, Widschwendter M, McGowan CH, Reed SI. Liberal V, et al. Among authors: spruck ch. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2754-9. doi: 10.1073/pnas.1102434108. Epub 2011 Jun 22. Proc Natl Acad Sci U S A. 2012. PMID: 21697511 Free PMC article.

10

PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.

Tan Y, Sun D, Jiang W, Klotz-Noack K, Vashisht AA, Wohlschlegel J, Widschwendter M, Spruck C. Tan Y, et al. Cancer Res. 2014 Apr 1;74(7):2006-14. doi: 10.1158/0008-5472.CAN-13-1263. Epub 2014 Feb 7. Cancer Res. 2014. PMID: 24509904 Free PMC article.

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