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An age-related increase in the number of CD8+ T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness.
Ouyang Q, Wagner WM, Walter S, Müller CA, Wikby A, Aubert G, Klatt T, Stevanovic S, Dodi T, Pawelec G. Ouyang Q, et al. Among authors: wagner wm. Mech Ageing Dev. 2003 Apr;124(4):477-85. doi: 10.1016/s0047-6374(03)00026-5. Mech Ageing Dev. 2003. PMID: 12714256
Pathways to a robust immune response in the elderly.
Pawelec G, Ouyang Q, Wagner W, Biol D, Wikby A. Pawelec G, et al. Immunol Allergy Clin North Am. 2003 Feb;23(1):1-13. doi: 10.1016/s0889-8561(02)00075-9. Immunol Allergy Clin North Am. 2003. PMID: 12645875 Review.
T cell immunosenescence in vitro and in vivo.
Pawelec G, Wagner W, Adibzadeh M, Engel A. Pawelec G, et al. Exp Gerontol. 1999 Jun;34(3):419-29. doi: 10.1016/s0531-5565(99)00002-9. Exp Gerontol. 1999. PMID: 10433396 Review.
38 results