McWilliams MJ - Search Results

1

Mutations at position 184 of human immunodeficiency virus type-1 reverse transcriptase affect virus titer and viral DNA synthesis.

Julias JG, Boyer PL, McWilliams MJ, Alvord WG, Hughes SH. Julias JG, et al. Among authors: mcwilliams mj. Virology. 2004 Apr 25;322(1):13-21. doi: 10.1016/j.virol.2004.01.004. Virology. 2004. PMID: 15063112 Free article.

2

Mutations in the human immunodeficiency virus type 1 polypurine tract (PPT) reduce the rate of PPT cleavage and plus-strand DNA synthesis.

McWilliams MJ, Julias JG, Hughes SH. McWilliams MJ, et al. J Virol. 2008 May;82(10):5104-8. doi: 10.1128/JVI.01897-07. Epub 2008 Mar 5. J Virol. 2008. PMID: 18321979 Free PMC article.

3

Mutations in the RNase H domain of HIV-1 reverse transcriptase affect the initiation of DNA synthesis and the specificity of RNase H cleavage in vivo.

Julias JG, McWilliams MJ, Sarafianos SG, Arnold E, Hughes SH. Julias JG, et al. Among authors: mcwilliams mj. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9515-20. doi: 10.1073/pnas.142123199. Epub 2002 Jul 1. Proc Natl Acad Sci U S A. 2002. PMID: 12093908 Free PMC article.

4

Mutation of amino acids in the connection domain of human immunodeficiency virus type 1 reverse transcriptase that contact the template-primer affects RNase H activity.

Julias JG, McWilliams MJ, Sarafianos SG, Alvord WG, Arnold E, Hughes SH. Julias JG, et al. Among authors: mcwilliams mj. J Virol. 2003 Aug;77(15):8548-54. doi: 10.1128/jvi.77.15.8548-8554.2003. J Virol. 2003. PMID: 12857924 Free PMC article.

5

Mutations in the 5' end of the human immunodeficiency virus type 1 polypurine tract affect RNase H cleavage specificity and virus titer.

McWilliams MJ, Julias JG, Sarafianos SG, Alvord WG, Arnold E, Hughes SH. McWilliams MJ, et al. J Virol. 2003 Oct;77(20):11150-7. doi: 10.1128/jvi.77.20.11150-11157.2003. J Virol. 2003. PMID: 14512562 Free PMC article.

6

Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavage.

Julias JG, McWilliams MJ, Sarafianos SG, Alvord WG, Arnold E, Hughes SH. Julias JG, et al. Among authors: mcwilliams mj. J Virol. 2004 Dec;78(23):13315-24. doi: 10.1128/JVI.78.23.13315-13324.2004. J Virol. 2004. PMID: 15542682 Free PMC article.

7

Combining mutations in HIV-1 reverse transcriptase with mutations in the HIV-1 polypurine tract affects RNase H cleavages involved in PPT utilization.

McWilliams MJ, Julias JG, Sarafianos SG, Alvord WG, Arnold E, Hughes SH. McWilliams MJ, et al. Virology. 2006 May 10;348(2):378-88. doi: 10.1016/j.virol.2005.12.042. Epub 2006 Feb 10. Virology. 2006. PMID: 16473384 Free article.

8

Mutations in the U5 region adjacent to the primer binding site affect tRNA cleavage by human immunodeficiency virus type 1 reverse transcriptase in vivo.

Oh J, McWilliams MJ, Julias JG, Hughes SH. Oh J, et al. Among authors: mcwilliams mj. J Virol. 2008 Jan;82(2):719-27. doi: 10.1128/JVI.02611-06. Epub 2007 Nov 7. J Virol. 2008. PMID: 17989171 Free PMC article.

9

Mutations in the thumb allow human immunodeficiency virus type 1 reverse transcriptase to be cleaved by protease in virions.

Dunn LL, McWilliams MJ, Das K, Arnold E, Hughes SH. Dunn LL, et al. Among authors: mcwilliams mj. J Virol. 2009 Dec;83(23):12336-44. doi: 10.1128/JVI.00676-09. Epub 2009 Sep 16. J Virol. 2009. PMID: 19759158 Free PMC article.

10

Treatment with suboptimal doses of raltegravir leads to aberrant HIV-1 integrations.

Varadarajan J, McWilliams MJ, Hughes SH. Varadarajan J, et al. Among authors: mcwilliams mj. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14747-52. doi: 10.1073/pnas.1305066110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959861 Free PMC article.

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