Dudda A - Search Results

1

Novel factor Xa inhibitors based on a benzoic acid scaffold and incorporating a neutral P1 ligand.

Nazaré M, Matter H, Klingler O, Al-Obeidi F, Schreuder H, Zoller G, Czech J, Lorenz M, Dudda A, Peyman A, Nestler HP, Urmann M, Bauer A, Laux V, Wehner V, Will DW. Nazaré M, et al. Among authors: dudda a. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2801-5. doi: 10.1016/j.bmcl.2004.03.059. Bioorg Med Chem Lett. 2004. PMID: 15125936

2

Factor Xa inhibitors based on a 2-carboxyindole scaffold: SAR of neutral P1 substituents.

Nazaré M, Essrich M, Will DW, Matter H, Ritter K, Urmann M, Bauer A, Schreuder H, Dudda A, Czech J, Lorenz M, Laux V, Wehner V. Nazaré M, et al. Among authors: dudda a. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4191-5. doi: 10.1016/j.bmcl.2004.06.020. Bioorg Med Chem Lett. 2004. PMID: 15261268

3

Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists.

Evers A, Haack T, Lorenz M, Bossart M, Elvert R, Henkel B, Stengelin S, Kurz M, Glien M, Dudda A, Lorenz K, Kadereit D, Wagner M. Evers A, et al. Among authors: dudda a. J Med Chem. 2017 May 25;60(10):4293-4303. doi: 10.1021/acs.jmedchem.7b00174. Epub 2017 May 5. J Med Chem. 2017. PMID: 28448133

4

Modulation of Hexadecyl-LPA-Mediated Activation of Mast Cells and Microglia by a Chemical Probe for LPA5.

Kozian DH, von Haeften E, Joho S, Czechtizky W, Anumala UR, Roux P, Dudda A, Evers A, Nazare M. Kozian DH, et al. Among authors: dudda a. Chembiochem. 2016 May 3;17(9):861-5. doi: 10.1002/cbic.201500559. Epub 2016 Mar 7. Chembiochem. 2016. PMID: 26812365

5

Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys.

Elvert R, Bossart M, Herling AW, Weiss T, Zhang B, Kannt A, Wagner M, Haack T, Evers A, Dudda A, Keil S, Lorenz M, Lorenz K, Riz M, Hennerici W, Larsen PJ. Elvert R, et al. Among authors: dudda a. Endocrinology. 2018 Aug 1;159(8):3105-3119. doi: 10.1210/en.2018-00399. Endocrinology. 2018. PMID: 29992313

6

Correction to Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonist.

Evers A, Haack T, Lorenz M, Bossart M, Elvert R, Henkel B, Stengelin S, Kurz M, Glien M, Dudda A, Lorenz K, Kadereit D, Wagner M. Evers A, et al. Among authors: dudda a. J Med Chem. 2017 Jul 13;60(13):5941. doi: 10.1021/acs.jmedchem.7b00887. Epub 2017 Jul 5. J Med Chem. 2017. PMID: 28677386 No abstract available.

7

Running on mixed fuel-dual agonistic approach of GLP-1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non-human primates.

Elvert R, Herling AW, Bossart M, Weiss T, Zhang B, Wenski P, Wandschneider J, Kleutsch S, Butty U, Kannt A, Wagner M, Haack T, Evers A, Dudda A, Lorenz M, Keil S, Larsen PJ. Elvert R, et al. Among authors: dudda a. Diabetes Obes Metab. 2018 Aug;20(8):1836-1851. doi: 10.1111/dom.13212. Epub 2018 Jun 25. Diabetes Obes Metab. 2018. PMID: 29938884 Free PMC article.

8

Mechanistic investigations of the liver toxicity of the free fatty acid receptor 1 agonist fasiglifam (TAK875) and its primary metabolites.

Ackerson T, Amberg A, Atzrodt J, Arabeyre C, Defossa E, Dorau M, Dudda A, Dwyer J, Holla W, Kissner T, Kohlmann M, Kürzel U, Pánczél J, Rajanna S, Riedel J, Schmidt F, Wäse K, Weitz D, Derdau V. Ackerson T, et al. Among authors: dudda a. J Biochem Mol Toxicol. 2019 Aug;33(8):e22345. doi: 10.1002/jbt.22345. Epub 2019 May 8. J Biochem Mol Toxicol. 2019. PMID: 31066974

9

Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction.

Taylor-Fishwick DA, Weaver J, Glenn L, Kuhn N, Rai G, Jadhav A, Simeonov A, Dudda A, Schmoll D, Holman TR, Maloney DJ, Nadler JL. Taylor-Fishwick DA, et al. Among authors: dudda a. Diabetologia. 2015 Mar;58(3):549-57. doi: 10.1007/s00125-014-3452-0. Epub 2014 Nov 23. Diabetologia. 2015. PMID: 25417214

10

Tuf of Streptococcus pneumoniae is a surface displayed human complement regulator binding protein.

Mohan S, Hertweck C, Dudda A, Hammerschmidt S, Skerka C, Hallström T, Zipfel PF. Mohan S, et al. Among authors: dudda a. Mol Immunol. 2014 Nov;62(1):249-64. doi: 10.1016/j.molimm.2014.06.029. Mol Immunol. 2014. PMID: 25046156

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