Matter H - Search Results

1

Novel factor Xa inhibitors based on a benzoic acid scaffold and incorporating a neutral P1 ligand.

Nazaré M, Matter H, Klingler O, Al-Obeidi F, Schreuder H, Zoller G, Czech J, Lorenz M, Dudda A, Peyman A, Nestler HP, Urmann M, Bauer A, Laux V, Wehner V, Will DW. Nazaré M, et al. Among authors: matter h. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2801-5. doi: 10.1016/j.bmcl.2004.03.059. Bioorg Med Chem Lett. 2004. PMID: 15125936

2

Selecting optimally diverse compounds from structure databases: a validation study of two-dimensional and three-dimensional molecular descriptors.

Matter H. Matter H. J Med Chem. 1997 Apr 11;40(8):1219-29. doi: 10.1021/jm960352+. J Med Chem. 1997. PMID: 9111296

3

Quantitative structure-activity relationship of human neutrophil collagenase (MMP-8) inhibitors using comparative molecular field analysis and X-ray structure analysis.

Matter H, Schwab W, Barbier D, Billen G, Haase B, Neises B, Schudok M, Thorwart W, Schreuder H, Brachvogel V, Lönze P, Weithmann KU. Matter H, et al. J Med Chem. 1999 Jun 3;42(11):1908-20. doi: 10.1021/jm980631s. J Med Chem. 1999. PMID: 10354399

4

Affinity and selectivity of matrix metalloproteinase inhibitors: a chemometrical study from the perspective of ligands and proteins.

Matter H, Schwab W. Matter H, et al. J Med Chem. 1999 Nov 4;42(22):4506-23. doi: 10.1021/jm990250u. J Med Chem. 1999. PMID: 10579815

5

Solid-phase optimisation of achiral amidinobenzyl indoles as potent and selective factor Xa inhibitors.

Heinelt U, Herok S, Matter H, Wildgoose P. Heinelt U, et al. Among authors: matter h. Bioorg Med Chem Lett. 2001 Jan 22;11(2):227-30. doi: 10.1016/s0960-894x(00)00631-4. Bioorg Med Chem Lett. 2001. PMID: 11206465

6

Structural classification of protein kinases using 3D molecular interaction field analysis of their ligand binding sites: target family landscapes.

Naumann T, Matter H. Naumann T, et al. Among authors: matter h. J Med Chem. 2002 Jun 6;45(12):2366-78. doi: 10.1021/jm011002c. J Med Chem. 2002. PMID: 12036347

7

Design and quantitative structure-activity relationship of 3-amidinobenzyl-1H-indole-2-carboxamides as potent, nonchiral, and selective inhibitors of blood coagulation factor Xa.

Matter H, Defossa E, Heinelt U, Blohm PM, Schneider D, Müller A, Herok S, Schreuder H, Liesum A, Brachvogel V, Lönze P, Walser A, Al-Obeidi F, Wildgoose P. Matter H, et al. J Med Chem. 2002 Jun 20;45(13):2749-69. doi: 10.1021/jm0111346. J Med Chem. 2002. PMID: 12061878

8

Structural requirements for inhibition of the neuronal nitric oxide synthase (NOS-I): 3D-QSAR analysis of 4-oxo- and 4-amino-pteridine-based inhibitors.

Matter H, Kotsonis P, Klingler O, Strobel H, Fröhlich LG, Frey A, Pfleiderer W, Schmidt HH. Matter H, et al. J Med Chem. 2002 Jul 4;45(14):2923-41. doi: 10.1021/jm020074g. J Med Chem. 2002. PMID: 12086480

9

Tetrahydroisoquinoline-3-carboxylate based matrix-metalloproteinase inhibitors: design, synthesis and structure-activity relationship.

Matter H, Schudok M, Schwab W, Thorwart W, Barbier D, Billen G, Haase B, Neises B, Weithmann K, Wollmann T. Matter H, et al. Bioorg Med Chem. 2002 Nov;10(11):3529-44. doi: 10.1016/s0968-0896(02)00215-8. Bioorg Med Chem. 2002. PMID: 12213468

10

Design, synthesis, and structure-activity relationship of a new class of amidinophenylurea-based factor VIIa inhibitors.

Klingler O, Matter H, Schudok M, Bajaj SP, Czech J, Lorenz M, Nestler HP, Schreuder H, Wildgoose P. Klingler O, et al. Among authors: matter h. Bioorg Med Chem Lett. 2003 Apr 17;13(8):1463-7. doi: 10.1016/s0960-894x(03)00168-9. Bioorg Med Chem Lett. 2003. PMID: 12668013

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