Young D - Search Results

1

VEGF links hippocampal activity with neurogenesis, learning and memory.

Cao L, Jiao X, Zuzga DS, Liu Y, Fong DM, Young D, During MJ. Cao L, et al. Among authors: young d. Nat Genet. 2004 Aug;36(8):827-35. doi: 10.1038/ng1395. Epub 2004 Jul 18. Nat Genet. 2004. PMID: 15258583

2

AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats.

Klugmann M, Symes CW, Leichtlein CB, Klaussner BK, Dunning J, Fong D, Young D, During MJ. Klugmann M, et al. Among authors: young d. Mol Cell Neurosci. 2005 Feb;28(2):347-60. doi: 10.1016/j.mcn.2004.10.002. Mol Cell Neurosci. 2005. PMID: 15691715

3

AAV-mediated overexpression of neuroserpin in the hippocampus decreases PSD-95 expression but does not affect hippocampal-dependent learning and memory.

Tsang VW, Young D, During MJ, Birch NP. Tsang VW, et al. Among authors: young d. PLoS One. 2014 Mar 7;9(3):e91050. doi: 10.1371/journal.pone.0091050. eCollection 2014. PLoS One. 2014. PMID: 24608243 Free PMC article.

4

A novel role of circadian transcription factor DBP in hippocampal plasticity.

Klugmann M, Leichtlein CB, Symes CW, Klaussner BC, Brooks AI, Young D, During MJ. Klugmann M, et al. Among authors: young d. Mol Cell Neurosci. 2006 Feb;31(2):303-14. doi: 10.1016/j.mcn.2005.09.019. Epub 2005 Oct 27. Mol Cell Neurosci. 2006. PMID: 16257226

5

Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective.

Young D, Lawlor PA, Leone P, Dragunow M, During MJ. Young D, et al. Nat Med. 1999 Apr;5(4):448-53. doi: 10.1038/7449. Nat Med. 1999. PMID: 10202938

6

Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy.

Young D, Fong DM, Lawlor PA, Wu A, Mouravlev A, McRae M, Glass M, Dragunow M, During MJ. Young D, et al. Gene Ther. 2014 Dec;21(12):1029-40. doi: 10.1038/gt.2014.82. Epub 2014 Sep 18. Gene Ther. 2014. PMID: 25231174 Free PMC article.

7

AAV-mediated gene delivery of BDNF or GDNF is neuroprotective in a model of Huntington disease.

Kells AP, Fong DM, Dragunow M, During MJ, Young D, Connor B. Kells AP, et al. Among authors: young d. Mol Ther. 2004 May;9(5):682-8. doi: 10.1016/j.ymthe.2004.02.016. Mol Ther. 2004. PMID: 15120329 Free article.

8

Somatic gene transfer of cAMP response element-binding protein attenuates memory impairment in aging rats.

Mouravlev A, Dunning J, Young D, During MJ. Mouravlev A, et al. Among authors: young d. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4705-10. doi: 10.1073/pnas.0506137103. Epub 2006 Mar 14. Proc Natl Acad Sci U S A. 2006. PMID: 16537429 Free PMC article.

9

Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial.

Kaplitt MG, Feigin A, Tang C, Fitzsimons HL, Mattis P, Lawlor PA, Bland RJ, Young D, Strybing K, Eidelberg D, During MJ. Kaplitt MG, et al. Among authors: young d. Lancet. 2007 Jun 23;369(9579):2097-105. doi: 10.1016/S0140-6736(07)60982-9. Lancet. 2007. PMID: 17586305 Clinical Trial.

10

Knockdown and overexpression of NR1 modulates NMDA receptor function.

Kalev-Zylinska ML, Symes W, Young D, During MJ. Kalev-Zylinska ML, et al. Among authors: young d. Mol Cell Neurosci. 2009 Aug;41(4):383-96. doi: 10.1016/j.mcn.2009.04.003. Epub 2009 Apr 24. Mol Cell Neurosci. 2009. PMID: 19394426 Free PMC article.

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