Jacques Y - Search Results

1

Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist.

Mortier E, Bernard J, Plet A, Jacques Y. Mortier E, et al. Among authors: jacques y. J Immunol. 2004 Aug 1;173(3):1681-8. doi: 10.4049/jimmunol.173.3.1681. J Immunol. 2004. PMID: 15265897

2

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins.

Mortier E, Quéméner A, Vusio P, Lorenzen I, Boublik Y, Grötzinger J, Plet A, Jacques Y. Mortier E, et al. Among authors: jacques y. J Biol Chem. 2006 Jan 20;281(3):1612-9. doi: 10.1074/jbc.M508624200. Epub 2005 Nov 11. J Biol Chem. 2006. PMID: 16284400 Free article.

3

The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha.

Bouchaud G, Garrigue-Antar L, Solé V, Quéméner A, Boublik Y, Mortier E, Perdreau H, Jacques Y, Plet A. Bouchaud G, et al. Among authors: jacques y. J Mol Biol. 2008 Sep 26;382(1):1-12. doi: 10.1016/j.jmb.2008.07.019. Epub 2008 Jul 16. J Mol Biol. 2008. PMID: 18656487

4

Cutting Edge: Differential Fine-Tuning of IL-2- and IL-15-Dependent Functions by Targeting Their Common IL-2/15Rβ/γc Receptor.

Meghnem D, Morisseau S, Frutoso M, Trillet K, Maillasson M, Barbieux I, Khaddage S, Leray I, Hildinger M, Quéméner A, Jacques Y, Mortier E. Meghnem D, et al. Among authors: jacques y. J Immunol. 2017 Jun 15;198(12):4563-4568. doi: 10.4049/jimmunol.1700046. Epub 2017 May 15. J Immunol. 2017. PMID: 28507024

5

Identification of an interleukin-15alpha receptor-binding site on human interleukin-15.

Bernard J, Harb C, Mortier E, Quéméner A, Meloen RH, Vermot-Desroches C, Wijdeness J, van Dijken P, Grötzinger J, Slootstra JW, Plet A, Jacques Y. Bernard J, et al. Among authors: jacques y. J Biol Chem. 2004 Jun 4;279(23):24313-22. doi: 10.1074/jbc.M312458200. Epub 2004 Mar 23. J Biol Chem. 2004. PMID: 15039446 Free article.

6

Docking of human interleukin-15 to its specific receptor alpha chain: correlation between molecular modeling and mutagenesis experimental data.

Quéméner A, Bernard J, Mortier E, Plet A, Jacques Y, Tran V. Quéméner A, et al. Among authors: jacques y. Proteins. 2006 Nov 15;65(3):623-36. doi: 10.1002/prot.21103. Proteins. 2006. PMID: 17001647

7

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo.

Huntington ND, Legrand N, Alves NL, Jaron B, Weijer K, Plet A, Corcuff E, Mortier E, Jacques Y, Spits H, Di Santo JP. Huntington ND, et al. Among authors: jacques y. J Exp Med. 2009 Jan 16;206(1):25-34. doi: 10.1084/jem.20082013. Epub 2008 Dec 22. J Exp Med. 2009. PMID: 19103877 Free PMC article.

8

Interleukin-15 and its soluble receptor mediate the response to infliximab in patients with Crohn's disease.

Bouchaud G, Mortier E, Flamant M, Barbieux I, Plet A, Galmiche JP, Jacques Y, Bourreille A. Bouchaud G, et al. Among authors: jacques y. Gastroenterology. 2010 Jun;138(7):2378-87. doi: 10.1053/j.gastro.2010.02.044. Epub 2010 Feb 23. Gastroenterology. 2010. PMID: 20188102

9

Different dynamics of IL-15R activation following IL-15 cis- or trans-presentation.

Perdreau H, Mortier E, Bouchaud G, Solé V, Boublik Y, Plet A, Jacques Y. Perdreau H, et al. Among authors: jacques y. Eur Cytokine Netw. 2010 Dec;21(4):297-307. doi: 10.1684/ecn.2010.0207. Epub 2010 Nov 16. Eur Cytokine Netw. 2010. PMID: 21078585 Free article.

10

IL-15.IL-15Rα complex shedding following trans-presentation is essential for the survival of IL-15 responding NK and T cells.

Tamzalit F, Barbieux I, Plet A, Heim J, Nedellec S, Morisseau S, Jacques Y, Mortier E. Tamzalit F, et al. Among authors: jacques y. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8565-70. doi: 10.1073/pnas.1405514111. Epub 2014 May 27. Proc Natl Acad Sci U S A. 2014. PMID: 24912180 Free PMC article.

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