Haynes RK - Search Results

1

Chiral bisphosphinite metalloligands derived from a P-chiral secondary phosphine oxide.

Chan EY, Zhang QF, Sau YK, Lo SM, Sung HH, Williams ID, Haynes RK, Leung WH. Chan EY, et al. Among authors: haynes rk. Inorg Chem. 2004 Aug 9;43(16):4921-6. doi: 10.1021/ic049744u. Inorg Chem. 2004. PMID: 15285668

2

Cocrystals of the antimalarial drug 11-azaartemisinin with three alkenoic acids of 1:1 or 2:1 stoichiometry.

Nisar M, Wong LWY, Sung HHY, Haynes RK, Williams ID. Nisar M, et al. Among authors: haynes rk. Acta Crystallogr C Struct Chem. 2018 Jun 1;74(Pt 6):742-751. doi: 10.1107/S2053229618006320. Epub 2018 May 24. Acta Crystallogr C Struct Chem. 2018. PMID: 29870011

3

Varying degrees of homostructurality in a series of cocrystals of antimalarial drug 11-azaartemisinin with salicylic acids.

Roy M, Li K, Nisar M, Wong LWY, Sung HHY, Haynes RK, Williams ID. Roy M, et al. Among authors: haynes rk. Acta Crystallogr C Struct Chem. 2021 Jun 1;77(Pt 6):262-270. doi: 10.1107/S2053229621004460. Epub 2021 May 6. Acta Crystallogr C Struct Chem. 2021. PMID: 34089249

4

Facile oxidation of leucomethylene blue and dihydroflavins by artemisinins: relationship with flavoenzyme function and antimalarial mechanism of action.

Haynes RK, Chan WC, Wong HN, Li KY, Wu WK, Fan KM, Sung HH, Williams ID, Prosperi D, Melato S, Coghi P, Monti D. Haynes RK, et al. ChemMedChem. 2010 Aug 2;5(8):1282-99. doi: 10.1002/cmdc.201000225. ChemMedChem. 2010. PMID: 20629071

5

Artesunate and dihydroartemisinin (DHA): unusual decomposition products formed under mild conditions and comments on the fitness of DHA as an antimalarial drug.

Haynes RK, Chan HW, Lung CM, Ng NC, Wong HN, Shek LY, Williams ID, Cartwright A, Gomes MF. Haynes RK, et al. ChemMedChem. 2007 Oct;2(10):1448-63. doi: 10.1002/cmdc.200700064. ChemMedChem. 2007. PMID: 17694524

6

Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities.

Haynes RK, Wong HN, Lee KW, Lung CM, Shek LY, Williams ID, Croft SL, Vivas L, Rattray L, Stewart L, Wong VK, Ko BC. Haynes RK, et al. ChemMedChem. 2007 Oct;2(10):1464-79. doi: 10.1002/cmdc.200700065. ChemMedChem. 2007. PMID: 17768731

7

Methylene Homologues of Artemisone: An Unexpected Structure-Activity Relationship and a Possible Implication for the Design of C10-Substituted Artemisinins.

Wu Y, Wu RW, Cheu KW, Williams ID, Krishna S, Slavic K, Gravett AM, Liu WM, Wong HN, Haynes RK. Wu Y, et al. Among authors: haynes rk. ChemMedChem. 2016 Jul 5;11(13):1469-79. doi: 10.1002/cmdc.201600011. Epub 2016 Jun 7. ChemMedChem. 2016. PMID: 27273875

8

Facile Preparation of N-Glycosylated 10-Piperazinyl Artemisinin Derivatives and Evaluation of Their Antimalarial and Cytotoxic Activities.

Wu Y, Parapini S, Williams ID, Misiano P, Wong HN, Taramelli D, Basilico N, Haynes RK. Wu Y, et al. Among authors: haynes rk. Molecules. 2018 Jul 13;23(7):1713. doi: 10.3390/molecules23071713. Molecules. 2018. PMID: 30011856 Free PMC article.

9

From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements.

Haynes RK. Haynes RK. Curr Top Med Chem. 2006;6(5):509-37. doi: 10.2174/156802606776743129. Curr Top Med Chem. 2006. PMID: 16719805 Review.

10

Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity.

Haynes RK, Ho WY, Chan HW, Fugmann B, Stetter J, Croft SL, Vivas L, Peters W, Robinson BL. Haynes RK, et al. Angew Chem Int Ed Engl. 2004 Mar 5;43(11):1381-5. doi: 10.1002/anie.200352343. Angew Chem Int Ed Engl. 2004. PMID: 15368412 No abstract available.

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