Tan Y - Search Results

1

Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate.

Yang Z, Sun X, Li S, Tan Y, Wang X, Zhang N, Yagi S, Takakura T, Kobayashi Y, Takimoto A, Yoshioka T, Suginaka A, Frenkel EP, Hoffman RM. Yang Z, et al. Among authors: tan y. Cancer Res. 2004 Aug 15;64(16):5775-8. doi: 10.1158/0008-5472.CAN-04-1406. Cancer Res. 2004. PMID: 15313919

2

In vivo efficacy of recombinant methioninase is enhanced by the combination of polyethylene glycol conjugation and pyridoxal 5'-phosphate supplementation.

Sun X, Yang Z, Li S, Tan Y, Zhang N, Wang X, Yagi S, Yoshioka T, Takimoto A, Mitsushima K, Suginaka A, Frenkel EP, Hoffman RM. Sun X, et al. Among authors: tan y. Cancer Res. 2003 Dec 1;63(23):8377-83. Cancer Res. 2003. PMID: 14678999

3

Pharmacokinetics, methionine depletion, and antigenicity of recombinant methioninase in primates.

Yang Z, Wang J, Yoshioka T, Li B, Lu Q, Li S, Sun X, Tan Y, Yagi S, Frenkel EP, Hoffman RM. Yang Z, et al. Among authors: tan y. Clin Cancer Res. 2004 Mar 15;10(6):2131-8. doi: 10.1158/1078-0432.ccr-03-0068. Clin Cancer Res. 2004. PMID: 15041734

4

Protein carboxyl amidation increases the potential extent of protein polyethylene glycol conjugation.

Li S, Yang Z, Sun X, Tan Y, Yagi S, Hoffman RM. Li S, et al. Among authors: tan y. Anal Biochem. 2004 Jul 15;330(2):264-71. doi: 10.1016/j.ab.2004.03.034. Anal Biochem. 2004. PMID: 15203332

5

PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates.

Yang Z, Wang J, Lu Q, Xu J, Kobayashi Y, Takakura T, Takimoto A, Yoshioka T, Lian C, Chen C, Zhang D, Zhang Y, Li S, Sun X, Tan Y, Yagi S, Frenkel EP, Hoffman RM. Yang Z, et al. Among authors: tan y. Cancer Res. 2004 Sep 15;64(18):6673-8. doi: 10.1158/0008-5472.CAN-04-1822. Cancer Res. 2004. PMID: 15374983

6

Broad selective efficacy of rMETase and PEG-rMETase on cancer cells in vitro.

Tan Y, Xu M, Hoffman RM. Tan Y, et al. Anticancer Res. 2010 Mar;30(3):793-8. Anticancer Res. 2010. Corrected and republished in: Anticancer Res. 2010 Apr;30(4):1041-6.. PMID: 20392998 Corrected and republished.

7

Broad selective efficacy of recombinant methioninase and polyethylene glycol-modified recombinant methioninase on cancer cells In Vitro.

Tan Y, Xu M, Hoffman RM. Tan Y, et al. Anticancer Res. 2010 Apr;30(4):1041-6. Anticancer Res. 2010. PMID: 20530407

8

Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer.

Kawaguchi K, Miyake K, Han Q, Li S, Tan Y, Igarashi K, Kiyuna T, Miyake M, Higuchi T, Oshiro H, Zhang Z, Razmjooei S, Wangsiricharoen S, Bouvet M, Singh SR, Unno M, Hoffman RM. Kawaguchi K, et al. Among authors: tan y. Cancer Lett. 2018 Sep 28;432:251-259. doi: 10.1016/j.canlet.2018.06.016. Epub 2018 Jun 18. Cancer Lett. 2018. PMID: 29928962

9

Development of Recombinant Methioninase for Cancer Treatment.

Hoffman RM, Tan Y, Li S, Han Q, Yagi S, Takakura T, Takimoto A, Inagaki K, Kudou D. Hoffman RM, et al. Among authors: tan y. Methods Mol Biol. 2019;1866:107-131. doi: 10.1007/978-1-4939-8796-2_10. Methods Mol Biol. 2019. PMID: 30725412

10

Safety and Toxicity of Recombinant Methioninase and Polyethylene Glycol (PEG) Recombinant Methioninase in Primates.

Hoffman RM, Yang Z, Tan Y, Han Q, Li S, Yagi S. Hoffman RM, et al. Among authors: tan y. Methods Mol Biol. 2019;1866:211-229. doi: 10.1007/978-1-4939-8796-2_16. Methods Mol Biol. 2019. PMID: 30725418

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