Mizwicki MT - Search Results

1

Identification of an alternative ligand-binding pocket in the nuclear vitamin D receptor and its functional importance in 1alpha,25(OH)2-vitamin D3 signaling.

Mizwicki MT, Keidel D, Bula CM, Bishop JE, Zanello LP, Wurtz JM, Moras D, Norman AW. Mizwicki MT, et al. Proc Natl Acad Sci U S A. 2004 Aug 31;101(35):12876-81. doi: 10.1073/pnas.0403606101. Epub 2004 Aug 23. Proc Natl Acad Sci U S A. 2004. PMID: 15326291 Free PMC article.

2

Molecular tools for study of genomic and rapid signal transduction responses initiated by 1 alpha,25(OH)(2)-vitamin D(3).

Norman AW, Bishop JE, Bula CM, Olivera CJ, Mizwicki MT, Zanello LP, Ishida H, Okamura WH. Norman AW, et al. Among authors: mizwicki mt. Steroids. 2002 May;67(6):457-66. doi: 10.1016/s0039-128x(01)00167-2. Steroids. 2002. PMID: 11960621 Review.

3

Two key proteins of the vitamin D endocrine system come into crystal clear focus: comparison of the X-ray structures of the nuclear receptor for 1alpha,25(OH)2 vitamin D3, the plasma vitamin D binding protein, and their ligands.

Mizwicki MT, Norman AW. Mizwicki MT, et al. J Bone Miner Res. 2003 May;18(5):795-806. doi: 10.1359/jbmr.2003.18.5.795. J Bone Miner Res. 2003. PMID: 12733718 Free article. No abstract available.

4

Evidence that annexin II is not a putative membrane receptor for 1alpha,25(OH)2-vitamin D3.

Mizwicki MT, Bishop JE, Olivera CJ, Huhtakangas J, Norman AW. Mizwicki MT, et al. J Cell Biochem. 2004 Mar 1;91(4):852-63. doi: 10.1002/jcb.10783. J Cell Biochem. 2004. PMID: 14991775

5

Applications of the Vitamin D sterol-Vitamin D receptor (VDR) conformational ensemble model.

Mizwicki MT, Bishop JE, Norman AW. Mizwicki MT, et al. Steroids. 2005 May-Jun;70(5-7):464-71. doi: 10.1016/j.steroids.2005.03.003. Epub 2005 Apr 8. Steroids. 2005. PMID: 15862832

6

A perspective on how the Vitamin D sterol/Vitamin D receptor (VDR) conformational ensemble model can potentially be used to understand the structure-function results of A-ring modified Vitamin D sterols.

Mizwicki MT, Bula CM, Bishop JE, Norman AW. Mizwicki MT, et al. J Steroid Biochem Mol Biol. 2005 Oct;97(1-2):69-82. doi: 10.1016/j.jsbmb.2005.06.025. Epub 2005 Aug 1. J Steroid Biochem Mol Biol. 2005. PMID: 16055325

7

New insights into Vitamin D sterol-VDR proteolysis, allostery, structure-function from the perspective of a conformational ensemble model.

Mizwicki MT, Bula CM, Bishop JE, Norman AW. Mizwicki MT, et al. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):243-62. doi: 10.1016/j.jsbmb.2006.12.004. J Steroid Biochem Mol Biol. 2007. PMID: 17368177 Free PMC article.

8

The vitamin D sterol-vitamin D receptor ensemble model offers unique insights into both genomic and rapid-response signaling.

Mizwicki MT, Norman AW. Mizwicki MT, et al. Sci Signal. 2009 Jun 16;2(75):re4. doi: 10.1126/scisignal.275re4. Sci Signal. 2009. PMID: 19531804 Review.

9

On the mechanism underlying (23S)-25-dehydro-1alpha(OH)-vitamin D3-26,23-lactone antagonism of hVDRwt gene activation and its switch to a superagonist.

Mizwicki MT, Bula CM, Mahinthichaichan P, Henry HL, Ishizuka S, Norman AW. Mizwicki MT, et al. J Biol Chem. 2009 Dec 25;284(52):36292-36301. doi: 10.1074/jbc.M109.042069. Epub 2009 Sep 28. J Biol Chem. 2009. PMID: 19801650 Free PMC article.

10

1alpha,25(OH)2-Vitamin D3 stimulation of secretion via chloride channel activation in Sertoli cells.

Menegaz D, Barrientos-Duran A, Kline A, Silva FR, Norman AW, Mizwicki MT, Zanello LP. Menegaz D, et al. Among authors: mizwicki mt. J Steroid Biochem Mol Biol. 2010 Apr;119(3-5):127-34. doi: 10.1016/j.jsbmb.2010.01.011. Epub 2010 Feb 13. J Steroid Biochem Mol Biol. 2010. PMID: 20156558

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