Gupta P - Search Results

1

Mechanistic aspects of mda-7/IL-24 cancer cell selectivity analysed via a bacterial fusion protein.

Sauane M, Gopalkrishnan RV, Choo HT, Gupta P, Lebedeva IV, Yacoub A, Dent P, Fisher PB. Sauane M, et al. Among authors: gupta p. Oncogene. 2004 Oct 7;23(46):7679-90. doi: 10.1038/sj.onc.1207958. Oncogene. 2004. PMID: 15334067

2

Ionizing radiation enhances therapeutic activity of mda-7/IL-24: overcoming radiation- and mda-7/IL-24-resistance in prostate cancer cells overexpressing the antiapoptotic proteins bcl-xL or bcl-2.

Su ZZ, Lebedeva IV, Sarkar D, Emdad L, Gupta P, Kitada S, Dent P, Reed JC, Fisher PB. Su ZZ, et al. Among authors: gupta p. Oncogene. 2006 Apr 13;25(16):2339-48. doi: 10.1038/sj.onc.1209271. Oncogene. 2006. PMID: 16331261

3

Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis.

Sauane M, Su ZZ, Gupta P, Lebedeva IV, Dent P, Sarkar D, Fisher PB. Sauane M, et al. Among authors: gupta p. Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9763-8. doi: 10.1073/pnas.0804089105. Epub 2008 Jul 3. Proc Natl Acad Sci U S A. 2008. PMID: 18599461 Free PMC article.

4

mda-7/IL-24: exploiting cancer's Achilles' heel.

Lebedeva IV, Sauane M, Gopalkrishnan RV, Sarkar D, Su ZZ, Gupta P, Nemunaitis J, Cunningham C, Yacoub A, Dent P, Fisher PB. Lebedeva IV, et al. Among authors: gupta p. Mol Ther. 2005 Jan;11(1):4-18. doi: 10.1016/j.ymthe.2004.08.012. Mol Ther. 2005. PMID: 15585401 Free article. Review.

5

Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.

Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, Fisher PB. Su Z, et al. Among authors: gupta p. Oncogene. 2005 Nov 17;24(51):7552-66. doi: 10.1038/sj.onc.1208911. Oncogene. 2005. PMID: 16044151

6

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine.

Gupta P, Su ZZ, Lebedeva IV, Sarkar D, Sauane M, Emdad L, Bachelor MA, Grant S, Curiel DT, Dent P, Fisher PB. Gupta P, et al. Pharmacol Ther. 2006 Sep;111(3):596-628. doi: 10.1016/j.pharmthera.2005.11.005. Epub 2006 Feb 7. Pharmacol Ther. 2006. PMID: 16464504 Free PMC article. Review.

7

Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer.

Emdad L, Sarkar D, Lebedeva IV, Su ZZ, Gupta P, Mahasreshti PJ, Dent P, Curiel DT, Fisher PB. Emdad L, et al. Among authors: gupta p. J Cell Physiol. 2006 Aug;208(2):298-306. doi: 10.1002/jcp.20663. J Cell Physiol. 2006. PMID: 16646087 Free PMC article.

8

BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis.

Gupta P, Walter MR, Su ZZ, Lebedeva IV, Emdad L, Randolph A, Valerie K, Sarkar D, Fisher PB. Gupta P, et al. Cancer Res. 2006 Aug 15;66(16):8182-91. doi: 10.1158/0008-5472.CAN-06-0577. Cancer Res. 2006. PMID: 16912197

9

Combinatorial treatment of non-small-cell lung cancers with gefitinib and Ad.mda-7 enhances apoptosis-induction and reverses resistance to a single therapy.

Emdad L, Lebedeva IV, Su ZZ, Gupta P, Sarkar D, Settleman J, Fisher PB. Emdad L, et al. Among authors: gupta p. J Cell Physiol. 2007 Feb;210(2):549-59. doi: 10.1002/jcp.20906. J Cell Physiol. 2007. PMID: 17111370

10

N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity.

Sauane M, Gupta P, Lebedeva IV, Su ZZ, Sarkar D, Randolph A, Valerie K, Gopalkrishnan RV, Fisher PB. Sauane M, et al. Among authors: gupta p. Cancer Res. 2006 Dec 15;66(24):11869-77. doi: 10.1158/0008-5472.CAN-06-1887. Cancer Res. 2006. PMID: 17178884

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