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Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.
Kawasaki Y, Kohno T, Zhuang ZY, Brenner GJ, Wang H, Van Der Meer C, Befort K, Woolf CJ, Ji RR. Kawasaki Y, et al. Among authors: brenner gj. J Neurosci. 2004 Sep 22;24(38):8310-21. doi: 10.1523/JNEUROSCI.2396-04.2004. J Neurosci. 2004. PMID: 15385614 Free PMC article.
Bradykinin and peripheral sensitization.
Wang H, Ehnert C, Brenner GJ, Woolf CJ. Wang H, et al. Among authors: brenner gj. Biol Chem. 2006 Jan;387(1):11-4. doi: 10.1515/BC.2006.003. Biol Chem. 2006. PMID: 16497159 Review.
Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.
Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, Reeh P, Kunos G, Kress M, Lutz B, Woolf CJ, Kuner R. Agarwal N, et al. Among authors: brenner gj. Nat Neurosci. 2007 Jul;10(7):870-9. doi: 10.1038/nn1916. Epub 2007 Jun 10. Nat Neurosci. 2007. PMID: 17558404 Free PMC article.
52 results