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APC and the three-hit hypothesis.
Segditsas S, Rowan AJ, Howarth K, Jones A, Leedham S, Wright NA, Gorman P, Chambers W, Domingo E, Roylance RR, Sawyer EJ, Sieber OM, Tomlinson IP. Segditsas S, et al. Oncogene. 2009 Jan 8;28(1):146-55. doi: 10.1038/onc.2008.361. Epub 2008 Oct 6. Oncogene. 2009. PMID: 18836487
Combined array-comparative genomic hybridization and single-nucleotide polymorphism-loss of heterozygosity analysis reveals complex changes and multiple forms of chromosomal instability in colorectal cancers.
Gaasenbeek M, Howarth K, Rowan AJ, Gorman PA, Jones A, Chaplin T, Liu Y, Bicknell D, Davison EJ, Fiegler H, Carter NP, Roylance RR, Tomlinson IP. Gaasenbeek M, et al. Cancer Res. 2006 Apr 1;66(7):3471-9. doi: 10.1158/0008-5472.CAN-05-3285. Cancer Res. 2006. PMID: 16585170
1,377 results