Williams KJ - Search Results

1

ZD6474, a potent inhibitor of vascular endothelial growth factor signaling, combined with radiotherapy: schedule-dependent enhancement of antitumor activity.

Williams KJ, Telfer BA, Brave S, Kendrew J, Whittaker L, Stratford IJ, Wedge SR. Williams KJ, et al. Clin Cancer Res. 2004 Dec 15;10(24):8587-93. doi: 10.1158/1078-0432.CCR-04-1147. Clin Cancer Res. 2004. PMID: 15623642

2

Hypoxia and oxidative stress. Tumour hypoxia--therapeutic considerations.

Williams KJ, Cowen RL, Stratford IJ. Williams KJ, et al. Breast Cancer Res. 2001;3(5):328-31. doi: 10.1186/bcr316. Epub 2001 Aug 7. Breast Cancer Res. 2001. PMID: 11597323 Free PMC article. Review.

3

Bioreductive and gene therapy approaches to hypoxic diseases.

Jaffar M, Williams KJ, Stratford IJ. Jaffar M, et al. Among authors: williams kj. Adv Drug Deliv Rev. 2001 Dec 17;53(2):217-28. doi: 10.1016/s0169-409x(01)00228-9. Adv Drug Deliv Rev. 2001. PMID: 11731027 Review.

4

A protective role for HIF-1 in response to redox manipulation and glucose deprivation: implications for tumorigenesis.

Williams KJ, Telfer BA, Airley RE, Peters HP, Sheridan MR, van der Kogel AJ, Harris AL, Stratford IJ. Williams KJ, et al. Oncogene. 2002 Jan 10;21(2):282-90. doi: 10.1038/sj.onc.1205047. Oncogene. 2002. PMID: 11803471

5

Synthesis and enzymatic evaluation of pyridinium-substituted uracil derivatives as novel inhibitors of thymidine phosphorylase.

Murray PE, McNally VA, Lockyer SD, Williams KJ, Stratford IJ, Jaffar M, Freeman S. Murray PE, et al. Among authors: williams kj. Bioorg Med Chem. 2002 Mar;10(3):525-30. doi: 10.1016/s0968-0896(01)00309-1. Bioorg Med Chem. 2002. PMID: 11814838

6

Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway.

Griffiths JR, McSheehy PM, Robinson SP, Troy H, Chung YL, Leek RD, Williams KJ, Stratford IJ, Harris AL, Stubbs M. Griffiths JR, et al. Among authors: williams kj. Cancer Res. 2002 Feb 1;62(3):688-95. Cancer Res. 2002. PMID: 11830521

7

Role of thymidine phosphorylase in an in vitro model of human bladder cancer invasion.

Jones A, Fujiyama C, Turner K, Cranston D, Williams K, Stratford I, Bicknell R, Harris AL. Jones A, et al. J Urol. 2002 Mar;167(3):1482-6. J Urol. 2002. PMID: 11832774

8

17beta-Oestradiol treatment modulates nitric oxide synthase activity in MDA231 tumour with implications on growth and radiation response.

Chinje EC, Williams KJ, Telfer BA, Wood PJ, van der Kogel AJ, Stratford IJ. Chinje EC, et al. Among authors: williams kj. Br J Cancer. 2002 Jan 7;86(1):136-42. doi: 10.1038/sj.bjc.6600032. Br J Cancer. 2002. PMID: 11857025 Free PMC article.

9

ZD1839 ('Iressa'), a specific oral epidermal growth factor receptor-tyrosine kinase inhibitor, potentiates radiotherapy in a human colorectal cancer xenograft model.

Williams KJ, Telfer BA, Stratford IJ, Wedge SR. Williams KJ, et al. Br J Cancer. 2002 Apr 8;86(7):1157-61. doi: 10.1038/sj.bjc.6600182. Br J Cancer. 2002. PMID: 11953865 Free PMC article.

10

Rescue of hypoxia-inducible factor-1alpha-deficient tumor growth by wild-type cells is independent of vascular endothelial growth factor.

Höpfl G, Wenger RH, Ziegler U, Stallmach T, Gardelle O, Achermann R, Wergin M, Kaser-Hotz B, Saunders HM, Williams KJ, Stratford IJ, Gassmann M, Desbaillets I. Höpfl G, et al. Among authors: williams kj. Cancer Res. 2002 May 15;62(10):2962-70. Cancer Res. 2002. PMID: 12019179

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