Kutok JL - Search Results

1

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

Mohi MG, Williams IR, Dearolf CR, Chan G, Kutok JL, Cohen S, Morgan K, Boulton C, Shigematsu H, Keilhack H, Akashi K, Gilliland DG, Neel BG. Mohi MG, et al. Among authors: kutok jl. Cancer Cell. 2005 Feb;7(2):179-91. doi: 10.1016/j.ccr.2005.01.010. Cancer Cell. 2005. PMID: 15710330 Free article.

2

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.

Araki T, Mohi MG, Ismat FA, Bronson RT, Williams IR, Kutok JL, Yang W, Pao LI, Gilliland DG, Epstein JA, Neel BG. Araki T, et al. Among authors: kutok jl. Nat Med. 2004 Aug;10(8):849-57. doi: 10.1038/nm1084. Epub 2004 Jul 25. Nat Med. 2004. PMID: 15273746

3

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Kelly L, Shigematsu H, Johnson L, Akashi K, Tuveson DA, Jacks T, Gilliland DG. Chan IT, et al. Among authors: kutok jl. J Clin Invest. 2004 Feb;113(4):528-38. doi: 10.1172/JCI20476. J Clin Invest. 2004. PMID: 14966562 Free PMC article.

4

Leukemogenic Ptpn11 causes fatal myeloproliferative disorder via cell-autonomous effects on multiple stages of hematopoiesis.

Chan G, Kalaitzidis D, Usenko T, Kutok JL, Yang W, Mohi MG, Neel BG. Chan G, et al. Among authors: kutok jl. Blood. 2009 Apr 30;113(18):4414-24. doi: 10.1182/blood-2008-10-182626. Epub 2009 Jan 29. Blood. 2009. PMID: 19179468 Free PMC article.

5

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells.

Chan G, Cheung LS, Yang W, Milyavsky M, Sanders AD, Gu S, Hong WX, Liu AX, Wang X, Barbara M, Sharma T, Gavin J, Kutok JL, Iscove NN, Shannon KM, Dick JE, Neel BG, Braun BS. Chan G, et al. Among authors: kutok jl. Blood. 2011 Apr 21;117(16):4253-61. doi: 10.1182/blood-2010-11-319517. Epub 2011 Feb 25. Blood. 2011. PMID: 21398220 Free PMC article.

6

MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.

Deguchi K, Ayton PM, Carapeti M, Kutok JL, Snyder CS, Williams IR, Cross NC, Glass CK, Cleary ML, Gilliland DG. Deguchi K, et al. Among authors: kutok jl. Cancer Cell. 2003 Mar;3(3):259-71. doi: 10.1016/s1535-6108(03)00051-5. Cancer Cell. 2003. PMID: 12676584 Free article.

7

PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease.

Cools J, Stover EH, Boulton CL, Gotlib J, Legare RD, Amaral SM, Curley DP, Duclos N, Rowan R, Kutok JL, Lee BH, Williams IR, Coutre SE, Stone RM, DeAngelo DJ, Marynen P, Manley PW, Meyer T, Fabbro D, Neuberg D, Weisberg E, Griffin JD, Gilliland DG. Cools J, et al. Among authors: kutok jl. Cancer Cell. 2003 May;3(5):459-69. doi: 10.1016/s1535-6108(03)00108-9. Cancer Cell. 2003. PMID: 12781364 Free article.

8

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model.

Kelly LM, Liu Q, Kutok JL, Williams IR, Boulton CL, Gilliland DG. Kelly LM, et al. Among authors: kutok jl. Blood. 2002 Jan 1;99(1):310-8. doi: 10.1182/blood.v99.1.310. Blood. 2002. PMID: 11756186 Free article.

9

Induction of myeloproliferative disease in mice by tyrosine kinase fusion oncogenes does not require granulocyte-macrophage colony-stimulating factor or interleukin-3.

Tomasson MH, Williams IR, Li S, Kutok J, Cain D, Gillessen S, Dranoff G, Van Etten RA, Gilliland DG. Tomasson MH, et al. Blood. 2001 Mar 1;97(5):1435-41. doi: 10.1182/blood.v97.5.1435. Blood. 2001. PMID: 11222391 Free article.

10

Positive and negative regulatory roles of the WW-like domain in TEL-PDGFbetaR transformation.

Chen J, Williams IR, Kutok JL, Duclos N, Anastasiadou E, Masters SC, Fu H, Gilliland DG. Chen J, et al. Among authors: kutok jl. Blood. 2004 Jul 15;104(2):535-42. doi: 10.1182/blood-2004-01-0169. Epub 2004 Mar 30. Blood. 2004. PMID: 15054045 Free article.

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