Williams IR - Search Results

1

Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations.

Mohi MG, Williams IR, Dearolf CR, Chan G, Kutok JL, Cohen S, Morgan K, Boulton C, Shigematsu H, Keilhack H, Akashi K, Gilliland DG, Neel BG. Mohi MG, et al. Among authors: williams ir. Cancer Cell. 2005 Feb;7(2):179-91. doi: 10.1016/j.ccr.2005.01.010. Cancer Cell. 2005. PMID: 15710330 Free article.

2

CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML).

Kelly LM, Yu JC, Boulton CL, Apatira M, Li J, Sullivan CM, Williams I, Amaral SM, Curley DP, Duclos N, Neuberg D, Scarborough RM, Pandey A, Hollenbach S, Abe K, Lokker NA, Gilliland DG, Giese NA. Kelly LM, et al. Cancer Cell. 2002 Jun;1(5):421-32. doi: 10.1016/s1535-6108(02)00070-3. Cancer Cell. 2002. PMID: 12124172 Free article.

3

Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.

Araki T, Mohi MG, Ismat FA, Bronson RT, Williams IR, Kutok JL, Yang W, Pao LI, Gilliland DG, Epstein JA, Neel BG. Araki T, et al. Among authors: williams ir. Nat Med. 2004 Aug;10(8):849-57. doi: 10.1038/nm1084. Epub 2004 Jul 25. Nat Med. 2004. PMID: 15273746

4

PKC412 overcomes resistance to imatinib in a murine model of FIP1L1-PDGFRα-induced myeloproliferative disease.

Cools J, Stover EH, Boulton CL, Gotlib J, Legare RD, Amaral SM, Curley DP, Duclos N, Rowan R, Kutok JL, Lee BH, Williams IR, Coutre SE, Stone RM, DeAngelo DJ, Marynen P, Manley PW, Meyer T, Fabbro D, Neuberg D, Weisberg E, Griffin JD, Gilliland DG. Cools J, et al. Among authors: williams ir. Cancer Cell. 2003 May;3(5):459-69. doi: 10.1016/s1535-6108(03)00108-9. Cancer Cell. 2003. PMID: 12781364 Free article.

5

FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model.

Kelly LM, Liu Q, Kutok JL, Williams IR, Boulton CL, Gilliland DG. Kelly LM, et al. Among authors: williams ir. Blood. 2002 Jan 1;99(1):310-8. doi: 10.1182/blood.v99.1.310. Blood. 2002. PMID: 11756186 Free article.

6

MOZ-TIF2-induced acute myeloid leukemia requires the MOZ nucleosome binding motif and TIF2-mediated recruitment of CBP.

Deguchi K, Ayton PM, Carapeti M, Kutok JL, Snyder CS, Williams IR, Cross NC, Glass CK, Cleary ML, Gilliland DG. Deguchi K, et al. Among authors: williams ir. Cancer Cell. 2003 Mar;3(3):259-71. doi: 10.1016/s1535-6108(03)00051-5. Cancer Cell. 2003. PMID: 12676584 Free article.

7

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease.

Chan IT, Kutok JL, Williams IR, Cohen S, Kelly L, Shigematsu H, Johnson L, Akashi K, Tuveson DA, Jacks T, Gilliland DG. Chan IT, et al. Among authors: williams ir. J Clin Invest. 2004 Feb;113(4):528-38. doi: 10.1172/JCI20476. J Clin Invest. 2004. PMID: 14966562 Free PMC article.

8

MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors.

Huntly BJ, Shigematsu H, Deguchi K, Lee BH, Mizuno S, Duclos N, Rowan R, Amaral S, Curley D, Williams IR, Akashi K, Gilliland DG. Huntly BJ, et al. Among authors: williams ir. Cancer Cell. 2004 Dec;6(6):587-96. doi: 10.1016/j.ccr.2004.10.015. Cancer Cell. 2004. PMID: 15607963 Free article.

9

Ott1(Rbm15) has pleiotropic roles in hematopoietic development.

Raffel GD, Mercher T, Shigematsu H, Williams IR, Cullen DE, Akashi K, Bernard OA, Gilliland DG. Raffel GD, et al. Among authors: williams ir. Proc Natl Acad Sci U S A. 2007 Apr 3;104(14):6001-6. doi: 10.1073/pnas.0609041104. Epub 2007 Mar 21. Proc Natl Acad Sci U S A. 2007. PMID: 17376872 Free PMC article.

10

A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9.

Dash AB, Williams IR, Kutok JL, Tomasson MH, Anastasiadou E, Lindahl K, Li S, Van Etten RA, Borrow J, Housman D, Druker B, Gilliland DG. Dash AB, et al. Among authors: williams ir. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7622-7. doi: 10.1073/pnas.102583199. Proc Natl Acad Sci U S A. 2002. PMID: 12032333 Free PMC article.

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