Botma GJ - Search Results

1

Sterol-regulatory-element binding protein inhibits upstream stimulatory factor-stimulated hepatic lipase gene expression.

Botma GJ, van Deursen D, Vieira D, van Hoek M, Jansen H, Verhoeven AJ. Botma GJ, et al. Atherosclerosis. 2005 Mar;179(1):61-7. doi: 10.1016/j.atherosclerosis.2004.10.027. Epub 2004 Dec 18. Atherosclerosis. 2005. PMID: 15721010

2

Transient induction of a variant hepatic lipase messenger RNA by corticotropic hormone in rat adrenals.

Botma GJ, Vieira D, Heuveling M, Jansen H, Verhoeven AJ. Botma GJ, et al. Metabolism. 2006 Apr;55(4):467-77. doi: 10.1016/j.metabol.2005.10.008. Metabolism. 2006. PMID: 16546477

3

Cloning, expression, and promoter analysis of hepatic lipase derived from human hyperplastic adrenals: evidence for alternative mRNA splicing.

Botma GJ, Heuveling M, Lamers JM, Jansen H, Verhoeven AJ. Botma GJ, et al. Cell Biochem Biophys. 2007;47(1):149-58. doi: 10.1385/cbb:47:1:149. Cell Biochem Biophys. 2007. PMID: 17406067

4

Comparative genomics and experimental promoter analysis reveal functional liver-specific elements in mammalian hepatic lipase genes.

van Deursen D, Botma GJ, Jansen H, Verhoeven AJ. van Deursen D, et al. Among authors: botma gj. BMC Genomics. 2007 Apr 11;8:99. doi: 10.1186/1471-2164-8-99. BMC Genomics. 2007. PMID: 17428321 Free PMC article.

5

High HDL cholesterol does not protect against coronary artery disease when associated with combined cholesteryl ester transfer protein and hepatic lipase gene variants.

van Acker BA, Botma GJ, Zwinderman AH, Kuivenhoven JA, Dallinga-Thie GM, Sijbrands EJ, Boer JM, Seidell JC, Jukema JW, Kastelein JJ, Jansen H, Verhoeven AJ; REGRESS Study Group. van Acker BA, et al. Among authors: botma gj. Atherosclerosis. 2008 Sep;200(1):161-7. doi: 10.1016/j.atherosclerosis.2007.11.019. Epub 2007 Dec 27. Atherosclerosis. 2008. PMID: 18164013 Clinical Trial.

6

Down-regulation of hepatic lipase expression by elevation of cAMP in human hepatoma but not adrenocortical cells.

van Deursen D, Botma GJ, Jansen H, Verhoeven AJ. van Deursen D, et al. Among authors: botma gj. Mol Cell Endocrinol. 2008 Nov 6;294(1-2):37-44. doi: 10.1016/j.mce.2008.07.004. Epub 2008 Jul 15. Mol Cell Endocrinol. 2008. PMID: 18675312 Free article.

7

Hepatic lipase promoter activity is reduced by the C-480T and G-216A substitutions present in the common LIPC gene variant, and is increased by Upstream Stimulatory Factor.

Botma GJ, Verhoeven AJ, Jansen H. Botma GJ, et al. Atherosclerosis. 2001 Feb 15;154(3):625-32. doi: 10.1016/s0021-9150(00)00478-0. Atherosclerosis. 2001. PMID: 11257263

8

Heterogeneity at the CETP gene locus. Influence on plasma CETP concentrations and HDL cholesterol levels.

Kuivenhoven JA, de Knijff P, Boer JM, Smalheer HA, Botma GJ, Seidell JC, Kastelein JJ, Pritchard PH. Kuivenhoven JA, et al. Among authors: botma gj. Arterioscler Thromb Vasc Biol. 1997 Mar;17(3):560-8. doi: 10.1161/01.atv.17.3.560. Arterioscler Thromb Vasc Biol. 1997. PMID: 9102177

9

A common mutation in the lipoprotein lipase gene (N291S) alters the lipoprotein phenotype and risk for cardiovascular disease in patients with familial hypercholesterolemia.

Wittekoek ME, Pimstone SN, Reymer PW, Feuth L, Botma GJ, Defesche JC, Prins M, Hayden MR, Kastelein JJ. Wittekoek ME, et al. Among authors: botma gj. Circulation. 1998 Mar 3;97(8):729-35. doi: 10.1161/01.cir.97.8.729. Circulation. 1998. PMID: 9498535

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