Arend M - Search Results

1

Stimulation of HIF-1alpha, HIF-2alpha, and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells.

Asikainen TM, Ahmad A, Schneider BK, Ho WB, Arend M, Brenner M, Günzler V, White CW. Asikainen TM, et al. Among authors: arend m. Free Radic Biol Med. 2005 Apr 15;38(8):1002-13. doi: 10.1016/j.freeradbiomed.2004.12.004. Free Radic Biol Med. 2005. PMID: 15780758

2

Preconditional activation of hypoxia-inducible factors ameliorates ischemic acute renal failure.

Bernhardt WM, Câmpean V, Kany S, Jürgensen JS, Weidemann A, Warnecke C, Arend M, Klaus S, Günzler V, Amann K, Willam C, Wiesener MS, Eckardt KU. Bernhardt WM, et al. Among authors: arend m. J Am Soc Nephrol. 2006 Jul;17(7):1970-8. doi: 10.1681/ASN.2005121302. Epub 2006 Jun 8. J Am Soc Nephrol. 2006. PMID: 16762988

3

Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease.

Del Balzo U, Signore PE, Walkinshaw G, Seeley TW, Brenner MC, Wang Q, Guo G, Arend MP, Flippin LA, Chow FA, Gervasi DC, Kjaergaard CH, Langsetmo I, Guenzler V, Liu DY, Klaus SJ, Lin A, Neff TB. Del Balzo U, et al. J Pharmacol Exp Ther. 2020 Aug;374(2):342-353. doi: 10.1124/jpet.120.265181. Epub 2020 Jun 2. J Pharmacol Exp Ther. 2020. PMID: 32487538

4

Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain.

Schneider C, Krischke G, Keller S, Walkinshaw G, Arend M, Rascher W, Gassmann M, Trollmann R. Schneider C, et al. Among authors: arend m. Brain Res. 2009 Jul 14;1280:43-51. doi: 10.1016/j.brainres.2009.05.023. Epub 2009 May 18. Brain Res. 2009. PMID: 19450570

5

Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization.

Paliege A, Rosenberger C, Bondke A, Sciesielski L, Shina A, Heyman SN, Flippin LA, Arend M, Klaus SJ, Bachmann S. Paliege A, et al. Among authors: arend m. Kidney Int. 2010 Feb;77(4):312-8. doi: 10.1038/ki.2009.460. Epub 2009 Dec 16. Kidney Int. 2010. PMID: 20016470 Free article.

6

Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis.

Laitala A, Aro E, Walkinshaw G, Mäki JM, Rossi M, Heikkilä M, Savolainen ER, Arend M, Kivirikko KI, Koivunen P, Myllyharju J. Laitala A, et al. Among authors: arend m. Blood. 2012 Oct 18;120(16):3336-44. doi: 10.1182/blood-2012-07-441824. Epub 2012 Sep 5. Blood. 2012. PMID: 22955912 Free article.

7

Donor treatment with a PHD-inhibitor activating HIFs prevents graft injury and prolongs survival in an allogenic kidney transplant model.

Bernhardt WM, Gottmann U, Doyon F, Buchholz B, Campean V, Schödel J, Reisenbuechler A, Klaus S, Arend M, Flippin L, Willam C, Wiesener MS, Yard B, Warnecke C, Eckardt KU. Bernhardt WM, et al. Among authors: arend m. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21276-81. doi: 10.1073/pnas.0903978106. Epub 2009 Nov 23. Proc Natl Acad Sci U S A. 2009. PMID: 19934037 Free PMC article.

8

Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney.

Rosenberger C, Rosen S, Shina A, Frei U, Eckardt KU, Flippin LA, Arend M, Klaus SJ, Heyman SN. Rosenberger C, et al. Among authors: arend m. Nephrol Dial Transplant. 2008 Nov;23(11):3472-8. doi: 10.1093/ndt/gfn276. Epub 2008 May 29. Nephrol Dial Transplant. 2008. PMID: 18515655

9

Differential effects of pharmacological HIF preconditioning of donors versus recipients in rat cardiac allografts.

Keränen MA, Tuuminen R, Syrjälä S, Krebs R, Walkinshaw G, Flippin LA, Arend M, Koskinen PK, Nykänen AI, Lemström KB. Keränen MA, et al. Among authors: arend m. Am J Transplant. 2013 Mar;13(3):600-10. doi: 10.1111/ajt.12064. Epub 2013 Jan 17. Am J Transplant. 2013. PMID: 23331861 Free article.

10

Non-hypoxic stabilization of hypoxia-inducible factor alpha (HIF-alpha): relevance in neural progenitor/stem cells.

Milosevic J, Adler I, Manaenko A, Schwarz SC, Walkinshaw G, Arend M, Flippin LA, Storch A, Schwarz J. Milosevic J, et al. Among authors: arend m. Neurotox Res. 2009 May;15(4):367-80. doi: 10.1007/s12640-009-9043-z. Epub 2009 Mar 20. Neurotox Res. 2009. PMID: 19384570

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