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Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.
Holdsworth G, Slocombe P, Doyle C, Sweeney B, Veverka V, Le Riche K, Franklin RJ, Compson J, Brookings D, Turner J, Kennedy J, Garlish R, Shi J, Newnham L, McMillan D, Muzylak M, Carr MD, Henry AJ, Ceska T, Robinson MK. Holdsworth G, et al. Among authors: slocombe p. J Biol Chem. 2012 Aug 3;287(32):26464-77. doi: 10.1074/jbc.M112.350108. Epub 2012 Jun 13. J Biol Chem. 2012. PMID: 22696217 Free PMC article.
Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.
Patel S, Barkell AM, Gupta D, Strong SL, Bruton S, Muskett FW, Addis PW, Renshaw PS, Slocombe PM, Doyle C, Clargo A, Taylor RJ, Prosser CE, Henry AJ, Robinson MK, Waters LC, Holdsworth G, Carr MD. Patel S, et al. Among authors: slocombe pm. J Biol Chem. 2018 Aug 3;293(31):12149-12166. doi: 10.1074/jbc.RA118.002918. Epub 2018 Jun 20. J Biol Chem. 2018. PMID: 29925589 Free PMC article.
Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation.
Veverka V, Henry AJ, Slocombe PM, Ventom A, Mulloy B, Muskett FW, Muzylak M, Greenslade K, Moore A, Zhang L, Gong J, Qian X, Paszty C, Taylor RJ, Robinson MK, Carr MD. Veverka V, et al. Among authors: slocombe pm. J Biol Chem. 2009 Apr 17;284(16):10890-900. doi: 10.1074/jbc.M807994200. Epub 2009 Feb 10. J Biol Chem. 2009. PMID: 19208630 Free PMC article.
The in vitro activity of ADAM-10 is inhibited by TIMP-1 and TIMP-3.
Amour A, Knight CG, Webster A, Slocombe PM, Stephens PE, Knäuper V, Docherty AJ, Murphy G. Amour A, et al. Among authors: slocombe pm. FEBS Lett. 2000 May 19;473(3):275-9. doi: 10.1016/s0014-5793(00)01528-3. FEBS Lett. 2000. PMID: 10818225 Free article.
TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3.
Amour A, Slocombe PM, Webster A, Butler M, Knight CG, Smith BJ, Stephens PE, Shelley C, Hutton M, Knäuper V, Docherty AJ, Murphy G. Amour A, et al. Among authors: slocombe pm. FEBS Lett. 1998 Sep 11;435(1):39-44. doi: 10.1016/s0014-5793(98)01031-x. FEBS Lett. 1998. PMID: 9755855 Free article.
35 results