Freeman MW - Search Results

1

Results from a Phase 1 Study Assessing the Pharmacokinetics of the Aldosterone Synthase Inhibitor Baxdrostat in Participants with Varying Degrees of Renal Function.

Freeman MW, Halvorsen YD, Bond M, Murphy B, Isaacsohn J. Freeman MW, et al. Clin Pharmacol Drug Dev. 2024 Apr;13(4):410-418. doi: 10.1002/cpdd.1371. Epub 2024 Feb 4. Clin Pharmacol Drug Dev. 2024. PMID: 38311833 Clinical Trial.

2

Meta-analysis of risk of major adverse cardiovascular events in adults with type 2 diabetes treated with bexagliflozin.

McMurray JJV, Solomon SD, Lock JP, Massaro JM, Zhu F, Zhou W, Skali H, Lewis EF, Freeman MW, Halvorsen YC. McMurray JJV, et al. Among authors: freeman mw. Diabetes Obes Metab. 2024 Mar;26(3):971-979. doi: 10.1111/dom.15394. Epub 2023 Dec 27. Diabetes Obes Metab. 2024. PMID: 38151752

3

Bexagliflozin as an adjunct to metformin for the treatment of type 2 diabetes in adults: A 24-week, randomized, double-blind, placebo-controlled trial.

Halvorsen YD, Conery AL, Lock JP, Zhou W, Freeman MW. Halvorsen YD, et al. Among authors: freeman mw. Diabetes Obes Metab. 2023 Oct;25(10):2954-2962. doi: 10.1111/dom.15192. Epub 2023 Jul 6. Diabetes Obes Metab. 2023. PMID: 37409573 Clinical Trial.

4

Baxdrostat for Treatment-Resistant Hypertension. Reply.

Freeman MW, Halvorsen YD, Brown MJ. Freeman MW, et al. N Engl J Med. 2023 May 11;388(19):1821-1822. doi: 10.1056/NEJMc2302673. N Engl J Med. 2023. PMID: 37163635 No abstract available.

5

Results From a Randomized, Open-Label, Crossover Study Evaluating the Effect of the Aldosterone Synthase Inhibitor Baxdrostat on the Pharmacokinetics of Metformin in Healthy Human Subjects.

Freeman MW, Bond M, Murphy B, Hui J, Isaacsohn J. Freeman MW, et al. Am J Cardiovasc Drugs. 2023 May;23(3):277-286. doi: 10.1007/s40256-023-00572-x. Epub 2023 Feb 15. Am J Cardiovasc Drugs. 2023. PMID: 36790596 Free PMC article. Clinical Trial.

6

Phase 2 Trial of Baxdrostat for Treatment-Resistant Hypertension.

Freeman MW, Halvorsen YD, Marshall W, Pater M, Isaacsohn J, Pearce C, Murphy B, Alp N, Srivastava A, Bhatt DL, Brown MJ; BrigHTN Investigators. Freeman MW, et al. N Engl J Med. 2023 Feb 2;388(5):395-405. doi: 10.1056/NEJMoa2213169. Epub 2022 Nov 7. N Engl J Med. 2023. PMID: 36342143 Clinical Trial.

7

Results from a phase 1, randomized, double-blind, multiple ascending dose study characterizing the pharmacokinetics and demonstrating the safety and selectivity of the aldosterone synthase inhibitor baxdrostat in healthy volunteers.

Freeman MW, Bond M, Murphy B, Hui J, Isaacsohn J. Freeman MW, et al. Hypertens Res. 2023 Jan;46(1):108-118. doi: 10.1038/s41440-022-01070-4. Epub 2022 Oct 20. Hypertens Res. 2023. PMID: 36266539 Free PMC article. Clinical Trial.

8

A 96-week, double-blind, randomized controlled trial comparing bexagliflozin to glimepiride as an adjunct to metformin for the treatment of type 2 diabetes in adults.

Halvorsen YD, Lock JP, Frias JP, Tinahones FJ, Dahl D, Conery AL, Freeman MW. Halvorsen YD, et al. Among authors: freeman mw. Diabetes Obes Metab. 2023 Jan;25(1):293-301. doi: 10.1111/dom.14875. Epub 2022 Oct 23. Diabetes Obes Metab. 2023. PMID: 36178197 Clinical Trial.

9

Correction for Jeyaseelan et al., "Distinct Roles of Pattern Recognition Receptors CD14 and Toll-Like Receptor 4 in Acute Lung Injury".

Jeyaseelan S, Chu HW, Young SK, Freeman MW, Worthen GS. Jeyaseelan S, et al. Among authors: freeman mw. Infect Immun. 2022 Apr 21;90(4):e0001422. doi: 10.1128/iai.00014-22. Epub 2022 Mar 14. Infect Immun. 2022. PMID: 35285245 Free PMC article. No abstract available.

10

Effects of low-dose naltrexone on quality of life in high-grade glioma patients: a placebo-controlled, double-blind randomized trial.

Peters KB, Affronti ML, Woodring S, Lipp E, Healy P, Herndon JE 2nd, Miller ES, Freeman MW, Randazzo DM, Desjardins A, Friedman HS. Peters KB, et al. Among authors: freeman mw. Support Care Cancer. 2022 Apr;30(4):3463-3471. doi: 10.1007/s00520-021-06738-0. Epub 2022 Jan 10. Support Care Cancer. 2022. PMID: 35001215 Clinical Trial.

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