Wrzesinski C - Search Results

1

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells.

Gattinoni L, Klebanoff CA, Palmer DC, Wrzesinski C, Kerstann K, Yu Z, Finkelstein SE, Theoret MR, Rosenberg SA, Restifo NP. Gattinoni L, et al. Among authors: wrzesinski c. J Clin Invest. 2005 Jun;115(6):1616-26. doi: 10.1172/JCI24480. J Clin Invest. 2005. PMID: 15931392 Free PMC article.

2

Vaccine-stimulated, adoptively transferred CD8+ T cells traffic indiscriminately and ubiquitously while mediating specific tumor destruction.

Palmer DC, Balasubramaniam S, Hanada K, Wrzesinski C, Yu Z, Farid S, Theoret MR, Hwang LN, Klebanoff CA, Gattinoni L, Goldstein AL, Yang JC, Restifo NP. Palmer DC, et al. Among authors: wrzesinski c. J Immunol. 2004 Dec 15;173(12):7209-16. doi: 10.4049/jimmunol.173.12.7209. J Immunol. 2004. PMID: 15585842 Free PMC article.

3

Less is more: lymphodepletion followed by hematopoietic stem cell transplant augments adoptive T-cell-based anti-tumor immunotherapy.

Wrzesinski C, Restifo NP. Wrzesinski C, et al. Curr Opin Immunol. 2005 Apr;17(2):195-201. doi: 10.1016/j.coi.2005.02.002. Curr Opin Immunol. 2005. PMID: 15766681 Free PMC article. Review.

4

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells.

Gattinoni L, Finkelstein SE, Klebanoff CA, Antony PA, Palmer DC, Spiess PJ, Hwang LN, Yu Z, Wrzesinski C, Heimann DM, Surh CD, Rosenberg SA, Restifo NP. Gattinoni L, et al. Among authors: wrzesinski c. J Exp Med. 2005 Oct 3;202(7):907-12. doi: 10.1084/jem.20050732. J Exp Med. 2005. PMID: 16203864 Free PMC article.

5

Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?

Muranski P, Boni A, Wrzesinski C, Citrin DE, Rosenberg SA, Childs R, Restifo NP. Muranski P, et al. Among authors: wrzesinski c. Nat Clin Pract Oncol. 2006 Dec;3(12):668-81. doi: 10.1038/ncponc0666. Nat Clin Pract Oncol. 2006. PMID: 17139318 Free PMC article. Review.

6

Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells.

Wrzesinski C, Paulos CM, Gattinoni L, Palmer DC, Kaiser A, Yu Z, Rosenberg SA, Restifo NP. Wrzesinski C, et al. J Clin Invest. 2007 Feb;117(2):492-501. doi: 10.1172/JCI30414. J Clin Invest. 2007. PMID: 17273561 Free PMC article.

7

Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.

Paulos CM, Wrzesinski C, Kaiser A, Hinrichs CS, Chieppa M, Cassard L, Palmer DC, Boni A, Muranski P, Yu Z, Gattinoni L, Antony PA, Rosenberg SA, Restifo NP. Paulos CM, et al. Among authors: wrzesinski c. J Clin Invest. 2007 Aug;117(8):2197-204. doi: 10.1172/JCI32205. J Clin Invest. 2007. PMID: 17657310 Free PMC article.

8

Toll-like receptors in tumor immunotherapy.

Paulos CM, Kaiser A, Wrzesinski C, Hinrichs CS, Cassard L, Boni A, Muranski P, Sanchez-Perez L, Palmer DC, Yu Z, Antony PA, Gattinoni L, Rosenberg SA, Restifo NP. Paulos CM, et al. Among authors: wrzesinski c. Clin Cancer Res. 2007 Sep 15;13(18 Pt 1):5280-9. doi: 10.1158/1078-0432.CCR-07-1378. Clin Cancer Res. 2007. PMID: 17875756 Free PMC article. Review.

9

Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity.

Palmer DC, Chan CC, Gattinoni L, Wrzesinski C, Paulos CM, Hinrichs CS, Powell DJ Jr, Klebanoff CA, Finkelstein SE, Fariss RN, Yu Z, Nussenblatt RB, Rosenberg SA, Restifo NP. Palmer DC, et al. Among authors: wrzesinski c. Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):8061-6. doi: 10.1073/pnas.0710929105. Epub 2008 Jun 3. Proc Natl Acad Sci U S A. 2008. PMID: 18523011 Free PMC article.

10

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells.

Gattinoni L, Zhong XS, Palmer DC, Ji Y, Hinrichs CS, Yu Z, Wrzesinski C, Boni A, Cassard L, Garvin LM, Paulos CM, Muranski P, Restifo NP. Gattinoni L, et al. Among authors: wrzesinski c. Nat Med. 2009 Jul;15(7):808-13. doi: 10.1038/nm.1982. Epub 2009 Jun 14. Nat Med. 2009. PMID: 19525962 Free PMC article.

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