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St. John's wort attenuates irinotecan-induced diarrhea via down-regulation of intestinal pro-inflammatory cytokines and inhibition of intestinal epithelial apoptosis.
Hu ZP, Yang XX, Chan SY, Xu AL, Duan W, Zhu YZ, Sheu FS, Boelsterli UA, Chan E, Zhang Q, Wang JC, Ee PL, Koh HL, Huang M, Zhou SF. Hu ZP, et al. Toxicol Appl Pharmacol. 2006 Oct 15;216(2):225-37. doi: 10.1016/j.taap.2006.05.020. Epub 2006 Jul 21. Toxicol Appl Pharmacol. 2006. PMID: 17015070
Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: application to cellular metabolism and accumulation studies.
Hu ZP, Yang XX, Chen X, Chan E, Duan W, Zhou SF. Hu ZP, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):575-80. doi: 10.1016/j.jchromb.2006.12.056. Epub 2007 Jan 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17270505
Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: application to plasma pharmacokinetic studies in the rat.
Yang X, Hu Z, Chan SY, Goh BC, Duan W, Chan E, Zhou S. Yang X, et al. Among authors: hu z. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jul 25;821(2):221-8. doi: 10.1016/j.jchromb.2005.05.010. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 15936253
Monitoring drug-protein interaction.
Yang XX, Hu ZP, Chan SY, Zhou SF. Yang XX, et al. Clin Chim Acta. 2006 Mar;365(1-2):9-29. doi: 10.1016/j.cca.2005.08.021. Epub 2005 Sep 30. Clin Chim Acta. 2006. PMID: 16199025 Review.
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