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509 results

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Page 1
Effects of (2R)-(3-amino-2-fluoropropyl)sulphinic acid (AFPSiA) on transient lower oesophageal sphincter relaxation in dogs and mechanism of hypothermic effects in mice.
Lehmann A, Holmberg AA, Bhatt U, Bremner-Danielsen M, Brändén L, Elg S, Elebring T, Fitzpatrick K, Geiss WB, Guzzo P, Jensen J, Jerndal G, Mattsson JP, Nilsson K, Olsson BM. Lehmann A, et al. Among authors: fitzpatrick k. Br J Pharmacol. 2005 Sep;146(1):89-97. doi: 10.1038/sj.bjp.0706299. Br J Pharmacol. 2005. PMID: 15980875 Free PMC article.
Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors.
Alstermark C, Amin K, Dinn SR, Elebring T, Fjellström O, Fitzpatrick K, Geiss WB, Gottfries J, Guzzo PR, Harding JP, Holmén A, Kothare M, Lehmann A, Mattsson JP, Nilsson K, Sundén G, Swanson M, von Unge S, Woo AM, Wyle MJ, Zheng X. Alstermark C, et al. Among authors: fitzpatrick k. J Med Chem. 2008 Jul 24;51(14):4315-20. doi: 10.1021/jm701425k. Epub 2008 Jun 25. J Med Chem. 2008. PMID: 18578471
5-Functionalized indazoles as glucocorticoid receptor agonists.
Bai M, Carr G, Deorazio RJ, Friedrich TD, Dobritsa S, Fitzpatrick K, Guzzo PR, Kitchen DB, Lynch MA, Peace D, Sajad M, Usyatinsky A, Wolf MA. Bai M, et al. Among authors: fitzpatrick k. Bioorg Med Chem Lett. 2010 May 15;20(10):3017-20. doi: 10.1016/j.bmcl.2010.04.012. Epub 2010 Apr 11. Bioorg Med Chem Lett. 2010. PMID: 20427184
Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome.
Manning DD, Cioffi CL, Usyatinsky A, Fitzpatrick K, Masih L, Guo C, Zhang Z, Choo SH, Sikkander MI, Ryan KN, Naginskaya J, Hassler C, Dobritsa S, Wierschke JD, Earley WG, Butler AS, Brady CA, Barnes NM, Cohen ML, Guzzo PR. Manning DD, et al. Among authors: fitzpatrick k. Bioorg Med Chem Lett. 2011 Jan 1;21(1):58-61. doi: 10.1016/j.bmcl.2010.11.080. Epub 2010 Nov 21. Bioorg Med Chem Lett. 2011. PMID: 21146988
The design and synthesis of novel SGLT2 inhibitors: C-glycosides with benzyltriazolopyridinone and phenylhydantoin as the aglycone moieties.
Guo C, Hu M, DeOrazio RJ, Usyatinsky A, Fitzpatrick K, Zhang Z, Maeng JH, Kitchen DB, Tom S, Luche M, Khmelnitsky Y, Mhyre AJ, Guzzo PR, Liu S. Guo C, et al. Among authors: fitzpatrick k. Bioorg Med Chem. 2014 Jul 1;22(13):3414-22. doi: 10.1016/j.bmc.2014.04.036. Epub 2014 Apr 28. Bioorg Med Chem. 2014. PMID: 24842618
Discovery of 2-substituted benzoxazole carboxamides as 5-HT3 receptor antagonists.
Yang Z, Fairfax DJ, Maeng JH, Masih L, Usyatinsky A, Hassler C, Isaacson S, Fitzpatrick K, DeOrazio RJ, Chen J, Harding JP, Isherwood M, Dobritsa S, Christensen KL, Wierschke JD, Bliss BI, Peterson LH, Beer CM, Cioffi C, Lynch M, Rennells WM, Richards JJ, Rust T, Khmelnitsky YL, Cohen ML, Manning DD. Yang Z, et al. Among authors: fitzpatrick k. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6538-41. doi: 10.1016/j.bmcl.2010.09.038. Epub 2010 Sep 16. Bioorg Med Chem Lett. 2010. PMID: 20889341
Effect of food on the pharmacokinetics of ropinirole in parkinsonian patients.
Brefel C, Thalamas C, Rayet S, Lopez-Gil A, Fitzpatrick K, Bullman S, Citerone DR, Taylor AC, Montastruc JL, Rascol O. Brefel C, et al. Among authors: fitzpatrick k. Br J Clin Pharmacol. 1998 Apr;45(4):412-5. doi: 10.1046/j.1365-2125.1998.t01-1-00704.x. Br J Clin Pharmacol. 1998. PMID: 9578193 Free PMC article. Clinical Trial.
509 results