Bigger BW - Search Results

1

Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX.

Bigger BW, Siapati EK, Mistry A, Waddington SN, Nivsarkar MS, Jacobs L, Perrett R, Holder MV, Ridler C, Kemball-Cook G, Ali RR, Forbes SJ, Coutelle C, Wright N, Alison M, Thrasher AJ, Bonnet D, Themis M. Bigger BW, et al. Gene Ther. 2006 Jan;13(2):117-26. doi: 10.1038/sj.gt.3302638. Gene Ther. 2006. PMID: 16163377

2

RETRACTED: Wiesinger et al. An Innovative Tool for Evidence-Based, Personalized Treatment Trials in Mucopolysaccharidosis. Pharmaceutics 2023, 15, 1565.

Wiesinger AM, Bigger B, Giugliani R, Lampe C, Scarpa M, Moser T, Kampmann C, Zimmermann G, Lagler FB. Wiesinger AM, et al. Pharmaceutics. 2023 Nov 7;15(11):2596. doi: 10.3390/pharmaceutics15112596. Pharmaceutics. 2023. PMID: 38004626 Free PMC article.

3

Improving newborn screening test performance for metachromatic leukodystrophy: Recommendation from a pre-pilot study that identified a late-infantile case for treatment.

Wu THY, Brown HA, Church HJ, Kershaw CJ, Hutton R, Egerton C, Cooper J, Tylee K, Cohen RN, Gokhale D, Ram D, Morton G, Henderson M, Bigger BW, Jones SA. Wu THY, et al. Among authors: bigger bw. Mol Genet Metab. 2024 May;142(1):108349. doi: 10.1016/j.ymgme.2024.108349. Epub 2024 Feb 20. Mol Genet Metab. 2024. PMID: 38458124 Free article.

4

An Innovative Tool for Evidence-Based, Personalized Treatment Trials in Mucopolysaccharidosis.

Wiesinger AM, Bigger B, Giugliani R, Lampe C, Scarpa M, Moser T, Kampmann C, Zimmermann G, Lagler FB. Wiesinger AM, et al. Pharmaceutics. 2023 May 22;15(5):1565. doi: 10.3390/pharmaceutics15051565. Pharmaceutics. 2023. Retraction in: Pharmaceutics. 2023 Nov 07;15(11):2596. doi: 10.3390/pharmaceutics15112596. PMID: 37242808 Free PMC article. Retracted.

5

Gene-modified neural progenitor cells for the treatment of neuropathic lysosomal storage diseases.

Mandolfo O, Bigger BW. Mandolfo O, et al. Among authors: bigger bw. Neural Regen Res. 2023 Sep;18(9):1954-1955. doi: 10.4103/1673-5374.367845. Neural Regen Res. 2023. PMID: 36926718 Free PMC article. No abstract available.

6

Collagen fibril formation at the plasma membrane occurs independently from collagen secretion.

Pickard A, Garva R, Adamson A, Calverley BC, Hoyle A, Hayward CE, Spiller D, Lu Y, Hodson N, Mandolfo O, Kim KK, Bou-Gharios G, Swift J, Bigger B, Kadler KE. Pickard A, et al. bioRxiv [Preprint]. 2024 May 10:2024.05.09.593302. doi: 10.1101/2024.05.09.593302. bioRxiv. 2024. PMID: 38766096 Free PMC article. Preprint.

7

Introduction of chloramphenicol resistance into the modified mouse mitochondrial genome: cloning of unstable sequences by passage through yeast.

Bigger B, Tolmachov O, Collombet JM, Coutelle C. Bigger B, et al. Anal Biochem. 2000 Jan 15;277(2):236-42. doi: 10.1006/abio.1999.4382. Anal Biochem. 2000. PMID: 10625512

8

Tipping the scales in favour of mitochondrial gene therapy.

Bigger B, Collombet JM, Coutelle C. Bigger B, et al. Gene Ther. 1999 Dec;6(12):1909-10. doi: 10.1038/sj.gt.3301090. Gene Ther. 1999. PMID: 10637441 No abstract available.

9

An araC-controlled bacterial cre expression system to produce DNA minicircle vectors for nuclear and mitochondrial gene therapy.

Bigger BW, Tolmachov O, Collombet JM, Fragkos M, Palaszewski I, Coutelle C. Bigger BW, et al. J Biol Chem. 2001 Jun 22;276(25):23018-27. doi: 10.1074/jbc.M010873200. Epub 2001 Apr 13. J Biol Chem. 2001. PMID: 11304530 Free article.

10

Perspectives on gene therapy for cystic fibrosis airway disease.

Bigger B, Coutelle C. Bigger B, et al. BioDrugs. 2001;15(9):615-34. doi: 10.2165/00063030-200115090-00006. BioDrugs. 2001. PMID: 11580305 Review.

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