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SLE peripheral blood B cell, T cell and myeloid cell transcriptomes display unique profiles and each subset contributes to the interferon signature.
Becker AM, Dao KH, Han BK, Kornu R, Lakhanpal S, Mobley AB, Li QZ, Lian Y, Wu T, Reimold AM, Olsen NJ, Karp DR, Chowdhury FZ, Farrar JD, Satterthwaite AB, Mohan C, Lipsky PE, Wakeland EK, Davis LS. Becker AM, et al. Among authors: karp dr. PLoS One. 2013 Jun 24;8(6):e67003. doi: 10.1371/journal.pone.0067003. Print 2013. PLoS One. 2013. PMID: 23826184 Free PMC article.
Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.
Raj P, Song R, Zhu H, Riediger L, Jun DJ, Liang C, Arana C, Zhang B, Gao Y, Wakeland BE, Dozmorov I, Zhou J, Kelly JA, Lauwerys BR, Guthridge JM, Olsen NJ, Nath SK, Pasare C, van Oers N, Gilkeson G, Tsao BP, Gaffney PM, Gregersen PK, James JA, Zuo X, Karp DR, Li QZ, Wakeland EK. Raj P, et al. Among authors: karp dr. Genome Biol. 2020 Nov 19;21(1):281. doi: 10.1186/s13059-020-02184-z. Genome Biol. 2020. PMID: 33213505 Free PMC article.
Risk factors for ANA positivity in healthy persons.
Li QZ, Karp DR, Quan J, Branch VK, Zhou J, Lian Y, Chong BF, Wakeland EK, Olsen NJ. Li QZ, et al. Among authors: karp dr. Arthritis Res Ther. 2011 Mar 2;13(2):R38. doi: 10.1186/ar3271. Arthritis Res Ther. 2011. PMID: 21366908 Free PMC article.
Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.
Sawalha AH, Kaufman KM, Kelly JA, Adler AJ, Aberle T, Kilpatrick J, Wakeland EK, Li QZ, Wandstrat AE, Karp DR, James JA, Merrill JT, Lipsky P, Harley JB. Sawalha AH, et al. Among authors: karp dr. Ann Rheum Dis. 2008 Apr;67(4):458-61. doi: 10.1136/ard.2007.075424. Epub 2007 Aug 24. Ann Rheum Dis. 2008. PMID: 17720724
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
Raj P, Rai E, Song R, Khan S, Wakeland BE, Viswanathan K, Arana C, Liang C, Zhang B, Dozmorov I, Carr-Johnson F, Mitrovic M, Wiley GB, Kelly JA, Lauwerys BR, Olsen NJ, Cotsapas C, Garcia CK, Wise CA, Harley JB, Nath SK, James JA, Jacob CO, Tsao BP, Pasare C, Karp DR, Li QZ, Gaffney PM, Wakeland EK. Raj P, et al. Among authors: karp dr. Elife. 2016 Feb 15;5:e12089. doi: 10.7554/eLife.12089. Elife. 2016. PMID: 26880555 Free PMC article.
148 results