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The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction.
Bacci S, Ludovico O, Prudente S, Zhang YY, Di Paola R, Mangiacotti D, Rauseo A, Nolan D, Duffy J, Fini G, Salvemini L, Amico C, Vigna C, Pellegrini F, Menzaghi C, Doria A, Trischitta V. Bacci S, et al. Among authors: zhang yy. Diabetes. 2005 Oct;54(10):3021-5. doi: 10.2337/diabetes.54.10.3021. Diabetes. 2005. PMID: 16186408
Association of the Q121 variant of ENPP1 gene with decreased kidney function among patients with type 2 diabetes.
De Cosmo S, Minenna A, Zhang YY, Thompson R, Miscio G, Vedovato M, Rauseo A, Saller A, Mastroianno S, Pellegrini F, Trevisan R, Fioretto P, Doria A, Trischitta V. De Cosmo S, et al. Among authors: zhang yy. Am J Kidney Dis. 2009 Feb;53(2):273-80. doi: 10.1053/j.ajkd.2008.07.040. Epub 2008 Oct 31. Am J Kidney Dis. 2009. PMID: 18950909 Free PMC article.
The ENPP1 Q121 variant predicts major cardiovascular events in high-risk individuals: evidence for interaction with obesity in diabetic patients.
Bacci S, Rizza S, Prudente S, Spoto B, Powers C, Facciorusso A, Pacilli A, Lauro D, Testa A, Zhang YY, Di Stolfo G, Mallamaci F, Tripepi G, Xu R, Mangiacotti D, Aucella F, Lauro R, Gervino EV, Hauser TH, Copetti M, De Cosmo S, Pellegrini F, Zoccali C, Federici M, Doria A, Trischitta V. Bacci S, et al. Among authors: zhang yy. Diabetes. 2011 Mar;60(3):1000-7. doi: 10.2337/db10-1300. Epub 2011 Jan 31. Diabetes. 2011. PMID: 21282363 Free PMC article.
The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.
Prudente S, Scarpelli D, Chandalia M, Zhang YY, Morini E, Del Guerra S, Perticone F, Li R, Powers C, Andreozzi F, Marchetti P, Dallapiccola B, Abate N, Doria A, Sesti G, Trischitta V. Prudente S, et al. Among authors: zhang yy. J Clin Endocrinol Metab. 2009 Jan;94(1):190-6. doi: 10.1210/jc.2008-1365. Epub 2008 Nov 4. J Clin Endocrinol Metab. 2009. PMID: 18984671 Free PMC article.
Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance.
Bacci S, Prudente S, Copetti M, Spoto B, Rizza S, Baratta R, Di Pietro N, Morini E, Di Paola R, Testa A, Mallamaci F, Tripepi G, Zhang YY, Mercuri L, Di Silvestre S, Lauro R, Malatino L, Consoli A, Pellegrini F, Pandolfi A, Frittitta L, Zoccali C, Federici M, Doria A, Trischitta V. Bacci S, et al. Among authors: zhang yy. Atherosclerosis. 2013 Jan;226(1):140-5. doi: 10.1016/j.atherosclerosis.2012.10.035. Epub 2012 Oct 16. Atherosclerosis. 2013. PMID: 23107043 Free PMC article.
3,178 results