Jacques Y - Search Results

1

Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins.

Mortier E, Quéméner A, Vusio P, Lorenzen I, Boublik Y, Grötzinger J, Plet A, Jacques Y. Mortier E, et al. Among authors: jacques y. J Biol Chem. 2006 Jan 20;281(3):1612-9. doi: 10.1074/jbc.M508624200. Epub 2005 Nov 11. J Biol Chem. 2006. PMID: 16284400 Free article.

2

Identification of an interleukin-15alpha receptor-binding site on human interleukin-15.

Bernard J, Harb C, Mortier E, Quéméner A, Meloen RH, Vermot-Desroches C, Wijdeness J, van Dijken P, Grötzinger J, Slootstra JW, Plet A, Jacques Y. Bernard J, et al. Among authors: jacques y. J Biol Chem. 2004 Jun 4;279(23):24313-22. doi: 10.1074/jbc.M312458200. Epub 2004 Mar 23. J Biol Chem. 2004. PMID: 15039446 Free article.

3

Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist.

Mortier E, Bernard J, Plet A, Jacques Y. Mortier E, et al. Among authors: jacques y. J Immunol. 2004 Aug 1;173(3):1681-8. doi: 10.4049/jimmunol.173.3.1681. J Immunol. 2004. PMID: 15265897

4

Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity.

Rabu C, Quéméner A, Jacques Y, Echasserieau K, Vusio P, Lang F. Rabu C, et al. Among authors: jacques y. J Biol Chem. 2005 Dec 16;280(50):41472-81. doi: 10.1074/jbc.M506881200. Epub 2005 Oct 4. J Biol Chem. 2005. PMID: 16204238 Free article.

5

The structure of the interleukin-15 alpha receptor and its implications for ligand binding.

Lorenzen I, Dingley AJ, Jacques Y, Grötzinger J. Lorenzen I, et al. Among authors: jacques y. J Biol Chem. 2006 Mar 10;281(10):6642-7. doi: 10.1074/jbc.M513118200. Epub 2005 Dec 23. J Biol Chem. 2006. PMID: 16377614 Free article.

6

Docking of human interleukin-15 to its specific receptor alpha chain: correlation between molecular modeling and mutagenesis experimental data.

Quéméner A, Bernard J, Mortier E, Plet A, Jacques Y, Tran V. Quéméner A, et al. Among authors: jacques y. Proteins. 2006 Nov 15;65(3):623-36. doi: 10.1002/prot.21103. Proteins. 2006. PMID: 17001647

7

The exon-3-encoded domain of IL-15ralpha contributes to IL-15 high-affinity binding and is crucial for the IL-15 antagonistic effect of soluble IL-15Ralpha.

Bouchaud G, Garrigue-Antar L, Solé V, Quéméner A, Boublik Y, Mortier E, Perdreau H, Jacques Y, Plet A. Bouchaud G, et al. Among authors: jacques y. J Mol Biol. 2008 Sep 26;382(1):1-12. doi: 10.1016/j.jmb.2008.07.019. Epub 2008 Jul 16. J Mol Biol. 2008. PMID: 18656487

8

Different dynamics of IL-15R activation following IL-15 cis- or trans-presentation.

Perdreau H, Mortier E, Bouchaud G, Solé V, Boublik Y, Plet A, Jacques Y. Perdreau H, et al. Among authors: jacques y. Eur Cytokine Netw. 2010 Dec;21(4):297-307. doi: 10.1684/ecn.2010.0207. Epub 2010 Nov 16. Eur Cytokine Netw. 2010. PMID: 21078585 Free article.

9

Characterization of a potent human interleukin-11 agonist.

Harmegnies D, Wang XM, Vandenbussche P, Leon A, Vusio P, Grötzinger J, Jacques Y, Goormaghtigh E, Devreese B, Content J. Harmegnies D, et al. Among authors: jacques y. Biochem J. 2003 Oct 1;375(Pt 1):23-32. doi: 10.1042/BJ20030459. Biochem J. 2003. PMID: 12919066 Free PMC article.

10

Soluble mannose 6-phosphate/insulin-like growth factor II (IGF-II) receptor inhibits interleukin-6-type cytokine-dependent proliferation by neutralization of IGF-II.

Duplomb L, Chaigne-Delalande B, Vusio P, Raher S, Jacques Y, Godard A, Blanchard F. Duplomb L, et al. Among authors: jacques y. Endocrinology. 2003 Dec;144(12):5381-9. doi: 10.1210/en.2003-0607. Epub 2003 Aug 28. Endocrinology. 2003. PMID: 12959977

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