O'keefe RJ - Search Results

1

Smad6 interacts with Runx2 and mediates Smad ubiquitin regulatory factor 1-induced Runx2 degradation.

Shen R, Chen M, Wang YJ, Kaneki H, Xing L, O'keefe RJ, Chen D. Shen R, et al. J Biol Chem. 2006 Feb 10;281(6):3569-76. doi: 10.1074/jbc.M506761200. Epub 2005 Nov 18. J Biol Chem. 2006. PMID: 16299379 Free PMC article.

2

PTHrP modulates chondrocyte differentiation through AP-1 and CREB signaling.

Ionescu AM, Schwarz EM, Vinson C, Puzas JE, Rosier R, Reynolds PR, O'Keefe RJ. Ionescu AM, et al. J Biol Chem. 2001 Apr 13;276(15):11639-47. doi: 10.1074/jbc.M006564200. Epub 2001 Jan 2. J Biol Chem. 2001. PMID: 11136722 Free article.

3

Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis.

Zhang X, Morham SG, Langenbach R, Young DA, Xing L, Boyce BF, Puzas EJ, Rosier RN, O'Keefe RJ, Schwarz EM. Zhang X, et al. J Bone Miner Res. 2001 Apr;16(4):660-70. doi: 10.1359/jbmr.2001.16.4.660. J Bone Miner Res. 2001. PMID: 11315993 Free article.

4

In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis.

Childs LM, Paschalis EP, Xing L, Dougall WC, Anderson D, Boskey AL, Puzas JE, Rosier RN, O'Keefe RJ, Boyce BF, Schwarz EM. Childs LM, et al. J Bone Miner Res. 2002 Feb;17(2):192-9. doi: 10.1359/jbmr.2002.17.2.192. J Bone Miner Res. 2002. PMID: 11811549 Free article.

5

A phage display technique identifies a novel regulator of cell differentiation.

Sheu TJ, Schwarz EM, Martinez DA, O'Keefe RJ, Rosier RN, Zuscik MJ, Puzas JE. Sheu TJ, et al. J Biol Chem. 2003 Jan 3;278(1):438-43. doi: 10.1074/jbc.M208292200. Epub 2002 Oct 25. J Biol Chem. 2003. PMID: 12403789 Free article.

6

Smad6 is induced by BMP-2 and modulates chondrocyte differentiation.

Li X, Ionescu AM, Schwarz EM, Zhang X, Drissi H, Puzas JE, Rosier RN, Zuscik MJ, O'Keefe RJ. Li X, et al. J Orthop Res. 2003 Sep;21(5):908-13. doi: 10.1016/S0736-0266(03)00008-1. J Orthop Res. 2003. PMID: 12919880 Free article.

7

Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes.

Drissi MH, Li X, Sheu TJ, Zuscik MJ, Schwarz EM, Puzas JE, Rosier RN, O'Keefe RJ. Drissi MH, et al. J Cell Biochem. 2003 Dec 15;90(6):1287-98. doi: 10.1002/jcb.10677. J Cell Biochem. 2003. PMID: 14635200

8

Systemic tumor necrosis factor alpha mediates an increase in peripheral CD11bhigh osteoclast precursors in tumor necrosis factor alpha-transgenic mice.

Li P, Schwarz EM, O'Keefe RJ, Ma L, Looney RJ, Ritchlin CT, Boyce BF, Xing L. Li P, et al. Arthritis Rheum. 2004 Jan;50(1):265-76. doi: 10.1002/art.11419. Arthritis Rheum. 2004. PMID: 14730625 Free article.

9

CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter.

Ionescu AM, Drissi H, Schwarz EM, Kato M, Puzas JE, McCance DJ, Rosier RN, Zuscik MJ, O'Keefe RJ. Ionescu AM, et al. J Cell Physiol. 2004 Mar;198(3):428-40. doi: 10.1002/jcp.10421. J Cell Physiol. 2004. PMID: 14755548

10

RANK signaling is not required for TNFalpha-mediated increase in CD11(hi) osteoclast precursors but is essential for mature osteoclast formation in TNFalpha-mediated inflammatory arthritis.

Li P, Schwarz EM, O'Keefe RJ, Ma L, Boyce BF, Xing L. Li P, et al. J Bone Miner Res. 2004 Feb;19(2):207-13. doi: 10.1359/JBMR.0301233. J Bone Miner Res. 2004. PMID: 14969390 Free article.

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