Liang Y - Search Results

1

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.

Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, West AB, Dawson VL, Dawson TM, Ross CA. Smith WW, et al. Among authors: liang y. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18676-81. doi: 10.1073/pnas.0508052102. Epub 2005 Dec 13. Proc Natl Acad Sci U S A. 2005. PMID: 16352719 Free PMC article.

2

G2019S-LRRK2 mutation enhances MPTP-linked Parkinsonism in mice.

Arbez N, He X, Huang Y, Ren M, Liang Y, Nucifora FC, Wang X, Pei Z, Tessarolo L, Smith WW, Ross CA. Arbez N, et al. Among authors: liang y. Hum Mol Genet. 2020 Mar 13;29(4):580-590. doi: 10.1093/hmg/ddz271. Hum Mol Genet. 2020. PMID: 31813996 Free PMC article.

3

Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin.

Jiang H, Poirier MA, Liang Y, Pei Z, Weiskittel CE, Smith WW, DeFranco DB, Ross CA. Jiang H, et al. Among authors: liang y. Neurobiol Dis. 2006 Sep;23(3):543-51. doi: 10.1016/j.nbd.2006.04.011. Neurobiol Dis. 2006. PMID: 16766198

4

Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death.

Jiang H, Wu YC, Nakamura M, Liang Y, Tanaka Y, Holmes S, Dawson VL, Dawson TM, Ross CA, Smith WW. Jiang H, et al. Among authors: liang y. Neurobiol Aging. 2007 Nov;28(11):1709-17. doi: 10.1016/j.neurobiolaging.2006.07.017. Epub 2006 Sep 15. Neurobiol Aging. 2007. PMID: 16978743

5

ATF3 plays a protective role against toxicity by N-terminal fragment of mutant huntingtin in stable PC12 cell line.

Liang Y, Jiang H, Ratovitski T, Jie C, Nakamura M, Hirschhorn RR, Wang X, Smith WW, Hai T, Poirier MA, Ross CA. Liang Y, et al. Brain Res. 2009 Aug 25;1286:221-9. doi: 10.1016/j.brainres.2009.06.049. Epub 2009 Jun 24. Brain Res. 2009. PMID: 19559011 Free PMC article.

6

Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model.

Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, Martin LJ, Moran TH, Lee MK, Borchelt DR, Ross CA. Smith WW, et al. Among authors: liang y. Hum Mol Genet. 2010 Jun 1;19(11):2087-98. doi: 10.1093/hmg/ddq086. Epub 2010 Feb 25. Hum Mol Genet. 2010. PMID: 20185556 Free PMC article.

7

Development and characterization of a new Parkinson's disease model resulting from impaired autophagy.

Ahmed I, Liang Y, Schools S, Dawson VL, Dawson TM, Savitt JM. Ahmed I, et al. Among authors: liang y. J Neurosci. 2012 Nov 14;32(46):16503-9. doi: 10.1523/JNEUROSCI.0209-12.2012. J Neurosci. 2012. PMID: 23152632 Free PMC article.

8

Mutant huntingtin N-terminal fragments of specific size mediate aggregation and toxicity in neuronal cells.

Ratovitski T, Gucek M, Jiang H, Chighladze E, Waldron E, D'Ambola J, Hou Z, Liang Y, Poirier MA, Hirschhorn RR, Graham R, Hayden MR, Cole RN, Ross CA. Ratovitski T, et al. Among authors: liang y. J Biol Chem. 2009 Apr 17;284(16):10855-67. doi: 10.1074/jbc.M804813200. Epub 2009 Feb 9. J Biol Chem. 2009. PMID: 19204007 Free PMC article.

9

N-terminal proteolysis of full-length mutant huntingtin in an inducible PC12 cell model of Huntington's disease.

Ratovitski T, Nakamura M, D'Ambola J, Chighladze E, Liang Y, Wang W, Graham R, Hayden MR, Borchelt DR, Hirschhorn RR, Ross CA. Ratovitski T, et al. Among authors: liang y. Cell Cycle. 2007 Dec 1;6(23):2970-81. doi: 10.4161/cc.6.23.4992. Cell Cycle. 2007. PMID: 18156806

10

Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease.

Masuda N, Peng Q, Li Q, Jiang M, Liang Y, Wang X, Zhao M, Wang W, Ross CA, Duan W. Masuda N, et al. Among authors: liang y. Neurobiol Dis. 2008 Jun;30(3):293-302. doi: 10.1016/j.nbd.2008.01.014. Epub 2008 Mar 10. Neurobiol Dis. 2008. PMID: 18395459 Free PMC article.

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