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Successful granulocyte-colony stimulating factor treatment of Crohn's disease is associated with the appearance of circulating interleukin-10-producing T cells and increased lamina propria plasmacytoid dendritic cells.
Mannon PJ, Leon F, Fuss IJ, Walter BA, Begnami M, Quezado M, Yang Z, Yi C, Groden C, Friend J, Hornung RL, Brown M, Gurprasad S, Kelsall B, Strober W. Mannon PJ, et al. Among authors: hornung rl. Clin Exp Immunol. 2009 Mar;155(3):447-56. doi: 10.1111/j.1365-2249.2008.03799.x. Epub 2008 Dec 15. Clin Exp Immunol. 2009. PMID: 19094118 Free PMC article.
Anti-interleukin-12 antibody for active Crohn's disease.
Mannon PJ, Fuss IJ, Mayer L, Elson CO, Sandborn WJ, Present D, Dolin B, Goodman N, Groden C, Hornung RL, Quezado M, Yang Z, Neurath MF, Salfeld J, Veldman GM, Schwertschlag U, Strober W; Anti-IL-12 Crohn's Disease Study Group. Mannon PJ, et al. Among authors: hornung rl. N Engl J Med. 2004 Nov 11;351(20):2069-79. doi: 10.1056/NEJMoa033402. N Engl J Med. 2004. PMID: 15537905 Free article. Clinical Trial.
Partial immune reconstitution of X-linked hyper IgM syndrome with recombinant CD40 ligand.
Jain A, Kovacs JA, Nelson DL, Migueles SA, Pittaluga S, Fanslow W, Fan X, Wong DW, Massey J, Hornung R, Brown MR, Spinner JJ, Liu S, Davey V, Hill HA, Ochs H, Fleisher TA. Jain A, et al. Blood. 2011 Oct 6;118(14):3811-7. doi: 10.1182/blood-2011-04-351254. Epub 2011 Aug 12. Blood. 2011. PMID: 21841160 Free PMC article. Clinical Trial.
CD40 agonist antibody mediated improvement of chronic Cryptosporidium infection in patients with X-linked hyper IgM syndrome.
Fan X, Upadhyaya B, Wu L, Koh C, Santín-Durán M, Pittaluga S, Uzel G, Kleiner D, Williams E, Ma CA, Bodansky A, Oliveira JB, Edmonds P, Hornung R, Wong DW, Fayer R, Fleisher T, Heller T, Prussin C, Jain A. Fan X, et al. Clin Immunol. 2012 May;143(2):152-61. doi: 10.1016/j.clim.2012.01.014. Epub 2012 Feb 7. Clin Immunol. 2012. PMID: 22459705 Free PMC article. Clinical Trial.
64 results