Jeong H - Search Results

1

In vitro analysis of huntingtin-mediated transcriptional repression reveals multiple transcription factor targets.

Zhai W, Jeong H, Cui L, Krainc D, Tjian R. Zhai W, et al. Among authors: jeong h. Cell. 2005 Dec 29;123(7):1241-53. doi: 10.1016/j.cell.2005.10.030. Cell. 2005. PMID: 16377565 Free article.

2

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N, Krainc D. Cui L, et al. Among authors: jeong h. Cell. 2006 Oct 6;127(1):59-69. doi: 10.1016/j.cell.2006.09.015. Cell. 2006. PMID: 17018277 Free article.

3

Acetylation targets mutant huntingtin to autophagosomes for degradation.

Jeong H, Then F, Melia TJ Jr, Mazzulli JR, Cui L, Savas JN, Voisine C, Paganetti P, Tanese N, Hart AC, Yamamoto A, Krainc D. Jeong H, et al. Cell. 2009 Apr 3;137(1):60-72. doi: 10.1016/j.cell.2009.03.018. Cell. 2009. PMID: 19345187 Free PMC article.

4

Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway.

Jeong H, Cohen DE, Cui L, Supinski A, Savas JN, Mazzulli JR, Yates JR 3rd, Bordone L, Guarente L, Krainc D. Jeong H, et al. Nat Med. 2011 Dec 18;18(1):159-65. doi: 10.1038/nm.2559. Nat Med. 2011. PMID: 22179316 Free PMC article.

5

Mutant Huntingtin Is Secreted via a Late Endosomal/Lysosomal Unconventional Secretory Pathway.

Trajkovic K, Jeong H, Krainc D. Trajkovic K, et al. Among authors: jeong h. J Neurosci. 2017 Sep 13;37(37):9000-9012. doi: 10.1523/JNEUROSCI.0118-17.2017. Epub 2017 Aug 16. J Neurosci. 2017. PMID: 28821645 Free PMC article.

6

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease.

Dunah AW, Jeong H, Griffin A, Kim YM, Standaert DG, Hersch SM, Mouradian MM, Young AB, Tanese N, Krainc D. Dunah AW, et al. Among authors: jeong h. Science. 2002 Jun 21;296(5576):2238-43. doi: 10.1126/science.1072613. Epub 2002 May 2. Science. 2002. PMID: 11988536

7

Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.

Al-Ramahi I, Giridharan SSP, Chen YC, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, Ferrer M, Southall N, Weisman LS, Botas J, Marugan JJ. Al-Ramahi I, et al. Among authors: jeong h. Elife. 2017 Dec 26;6:e29123. doi: 10.7554/eLife.29123. Elife. 2017. PMID: 29256861 Free PMC article.

8

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets.

Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, Zhang J, Mori S, Yang XW, Tamashiro KL, Aja S, Moran TH, Luthi-Carter R, Martin B, Maudsley S, Mattson MP, Cichewicz RH, Ross CA, Holtzman DM, Krainc D, Duan W. Jiang M, et al. Among authors: jeong h. Nat Med. 2011 Dec 18;18(1):153-8. doi: 10.1038/nm.2558. Nat Med. 2011. PMID: 22179319 Free PMC article.

9

Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease.

Xiang Z, Valenza M, Cui L, Leoni V, Jeong HK, Brilli E, Zhang J, Peng Q, Duan W, Reeves SA, Cattaneo E, Krainc D. Xiang Z, et al. J Neurosci. 2011 Jun 29;31(26):9544-53. doi: 10.1523/JNEUROSCI.1291-11.2011. J Neurosci. 2011. PMID: 21715619 Free PMC article.

10

Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors.

Kegel KB, Sapp E, Alexander J, Reeves P, Bleckmann D, Sobin L, Masso N, Valencia A, Jeong H, Krainc D, Palacino J, Curtis D, Kuhn R, Betschart C, Sena-Esteves M, Aronin N, Paganetti P, Difiglia M. Kegel KB, et al. Among authors: jeong h. Mol Neurodegener. 2010 Dec 14;5:58. doi: 10.1186/1750-1326-5-58. Mol Neurodegener. 2010. PMID: 21156064 Free PMC article.

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