Mazarakis ND - Search Results

1

Lentivirus-mediated gene transfer to the central nervous system: therapeutic and research applications.

Wong LF, Goodhead L, Prat C, Mitrophanous KA, Kingsman SM, Mazarakis ND. Wong LF, et al. Among authors: mazarakis nd. Hum Gene Ther. 2006 Jan;17(1):1-9. doi: 10.1089/hum.2006.17.1. Hum Gene Ther. 2006. PMID: 16409120 Review.

2

Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease.

Azzouz M, Martin-Rendon E, Barber RD, Mitrophanous KA, Carter EE, Rohll JB, Kingsman SM, Kingsman AJ, Mazarakis ND. Azzouz M, et al. Among authors: mazarakis nd. J Neurosci. 2002 Dec 1;22(23):10302-12. doi: 10.1523/JNEUROSCI.22-23-10302.2002. J Neurosci. 2002. PMID: 12451130 Free PMC article.

3

Transduction patterns of pseudotyped lentiviral vectors in the nervous system.

Wong LF, Azzouz M, Walmsley LE, Askham Z, Wilkes FJ, Mitrophanous KA, Kingsman SM, Mazarakis ND. Wong LF, et al. Among authors: mazarakis nd. Mol Ther. 2004 Jan;9(1):101-11. doi: 10.1016/j.ymthe.2003.09.017. Mol Ther. 2004. PMID: 14741783 Free article.

4

Lentiviral vectors for treating and modeling human CNS disorders.

Azzouz M, Kingsman SM, Mazarakis ND. Azzouz M, et al. Among authors: mazarakis nd. J Gene Med. 2004 Sep;6(9):951-62. doi: 10.1002/jgm.600. J Gene Med. 2004. PMID: 15352068 Review.

5

Lentiviral-mediated delivery of Bcl-2 or GDNF protects against excitotoxicity in the rat hippocampus.

Wong LF, Ralph GS, Walmsley LE, Bienemann AS, Parham S, Kingsman SM, Uney JB, Mazarakis ND. Wong LF, et al. Among authors: mazarakis nd. Mol Ther. 2005 Jan;11(1):89-95. doi: 10.1016/j.ymthe.2004.08.026. Mol Ther. 2005. PMID: 15585409 Free article.

6

Lentivector-mediated SMN replacement in a mouse model of spinal muscular atrophy.

Azzouz M, Le T, Ralph GS, Walmsley L, Monani UR, Lee DC, Wilkes F, Mitrophanous KA, Kingsman SM, Burghes AH, Mazarakis ND. Azzouz M, et al. Among authors: mazarakis nd. J Clin Invest. 2004 Dec;114(12):1726-31. doi: 10.1172/JCI22922. J Clin Invest. 2004. PMID: 15599397 Free PMC article.

7

Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery.

Mazarakis ND, Azzouz M, Rohll JB, Ellard FM, Wilkes FJ, Olsen AL, Carter EE, Barber RD, Baban DF, Kingsman SM, Kingsman AJ, O'Malley K, Mitrophanous KA. Mazarakis ND, et al. Hum Mol Genet. 2001 Sep 15;10(19):2109-21. doi: 10.1093/hmg/10.19.2109. Hum Mol Genet. 2001. PMID: 11590128

8

Stable gene transfer to the nervous system using a non-primate lentiviral vector.

Mitrophanous K, Yoon S, Rohll J, Patil D, Wilkes F, Kim V, Kingsman S, Kingsman A, Mazarakis N. Mitrophanous K, et al. Gene Ther. 1999 Nov;6(11):1808-18. doi: 10.1038/sj.gt.3301023. Gene Ther. 1999. PMID: 10602376

9

Design, production, safety, evaluation, and clinical applications of nonprimate lentiviral vectors.

Rohll JB, Mitrophanous KA, Martin-Rendon E, Ellard FM, Radcliffe PA, Mazarakis ND, Kingsman SM. Rohll JB, et al. Among authors: mazarakis nd. Methods Enzymol. 2002;346:466-500. doi: 10.1016/s0076-6879(02)46072-7. Methods Enzymol. 2002. PMID: 11883086 No abstract available.

10

New methods to titrate EIAV-based lentiviral vectors.

Martin-Rendon E, White LJ, Olsen A, Mitrophanous KA, Mazarakis ND. Martin-Rendon E, et al. Among authors: mazarakis nd. Mol Ther. 2002 May;5(5 Pt 1):566-70. doi: 10.1006/mthe.2002.0576. Mol Ther. 2002. PMID: 11991747 Free article.

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